Chemoradiotherapy for recurrent CBTs case report
Abstract Background Carotid body tumors (CBTs) are rare paragangliomas with an incidence of 1–2 per 100,000 individuals. While surgical resection remains the standard treatment, postoperative recurrence poses a clinical challenge. Case presentation We describe a 49-year-old female with recurrent CBT...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Springer
2025-08-01
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| Series: | Discover Oncology |
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| Online Access: | https://doi.org/10.1007/s12672-025-03386-2 |
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| _version_ | 1849764413466214400 |
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| author | Guangyu Liu Shuangyan Zhao Jiankai Wang Xiaoyu Duan Hongyi Cai |
| author_facet | Guangyu Liu Shuangyan Zhao Jiankai Wang Xiaoyu Duan Hongyi Cai |
| author_sort | Guangyu Liu |
| collection | DOAJ |
| description | Abstract Background Carotid body tumors (CBTs) are rare paragangliomas with an incidence of 1–2 per 100,000 individuals. While surgical resection remains the standard treatment, postoperative recurrence poses a clinical challenge. Case presentation We describe a 49-year-old female with recurrent CBT involving the jugular foramen, managed with IGRT (60 Gy/30 fractions) and 4 cycles of CVD chemotherapy. Post-treatment RECIST evaluation revealed stable disease, supporting chemoradiotherapy as a salvage option for anatomically complex recurrences. Conclusion This case underscores the necessity for standardized protocols and further research to validate multimodal therapy in recurrent CBTs. |
| format | Article |
| id | doaj-art-1af8ec15970548fea67efd20f9f10bc6 |
| institution | DOAJ |
| issn | 2730-6011 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Springer |
| record_format | Article |
| series | Discover Oncology |
| spelling | doaj-art-1af8ec15970548fea67efd20f9f10bc62025-08-20T03:05:09ZengSpringerDiscover Oncology2730-60112025-08-011611710.1007/s12672-025-03386-2Chemoradiotherapy for recurrent CBTs case reportGuangyu Liu0Shuangyan Zhao1Jiankai Wang2Xiaoyu Duan3Hongyi Cai4Gansu University of Chinese MedicineGansu University of Chinese MedicineDepartment of Radiotherapy, Gansu Provincal HospitalDepartment of Radiotherapy, Gansu Provincal HospitalDepartment of Radiotherapy, Gansu Provincal HospitalAbstract Background Carotid body tumors (CBTs) are rare paragangliomas with an incidence of 1–2 per 100,000 individuals. While surgical resection remains the standard treatment, postoperative recurrence poses a clinical challenge. Case presentation We describe a 49-year-old female with recurrent CBT involving the jugular foramen, managed with IGRT (60 Gy/30 fractions) and 4 cycles of CVD chemotherapy. Post-treatment RECIST evaluation revealed stable disease, supporting chemoradiotherapy as a salvage option for anatomically complex recurrences. Conclusion This case underscores the necessity for standardized protocols and further research to validate multimodal therapy in recurrent CBTs.https://doi.org/10.1007/s12672-025-03386-2Carotid body tumorChemoradiotherapyRecurrenceCVD regimen |
| spellingShingle | Guangyu Liu Shuangyan Zhao Jiankai Wang Xiaoyu Duan Hongyi Cai Chemoradiotherapy for recurrent CBTs case report Discover Oncology Carotid body tumor Chemoradiotherapy Recurrence CVD regimen |
| title | Chemoradiotherapy for recurrent CBTs case report |
| title_full | Chemoradiotherapy for recurrent CBTs case report |
| title_fullStr | Chemoradiotherapy for recurrent CBTs case report |
| title_full_unstemmed | Chemoradiotherapy for recurrent CBTs case report |
| title_short | Chemoradiotherapy for recurrent CBTs case report |
| title_sort | chemoradiotherapy for recurrent cbts case report |
| topic | Carotid body tumor Chemoradiotherapy Recurrence CVD regimen |
| url | https://doi.org/10.1007/s12672-025-03386-2 |
| work_keys_str_mv | AT guangyuliu chemoradiotherapyforrecurrentcbtscasereport AT shuangyanzhao chemoradiotherapyforrecurrentcbtscasereport AT jiankaiwang chemoradiotherapyforrecurrentcbtscasereport AT xiaoyuduan chemoradiotherapyforrecurrentcbtscasereport AT hongyicai chemoradiotherapyforrecurrentcbtscasereport |