Chemoradiotherapy for recurrent CBTs case report

Abstract Background Carotid body tumors (CBTs) are rare paragangliomas with an incidence of 1–2 per 100,000 individuals. While surgical resection remains the standard treatment, postoperative recurrence poses a clinical challenge. Case presentation We describe a 49-year-old female with recurrent CBT...

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Bibliographic Details
Main Authors: Guangyu Liu, Shuangyan Zhao, Jiankai Wang, Xiaoyu Duan, Hongyi Cai
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-03386-2
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Summary:Abstract Background Carotid body tumors (CBTs) are rare paragangliomas with an incidence of 1–2 per 100,000 individuals. While surgical resection remains the standard treatment, postoperative recurrence poses a clinical challenge. Case presentation We describe a 49-year-old female with recurrent CBT involving the jugular foramen, managed with IGRT (60 Gy/30 fractions) and 4 cycles of CVD chemotherapy. Post-treatment RECIST evaluation revealed stable disease, supporting chemoradiotherapy as a salvage option for anatomically complex recurrences. Conclusion This case underscores the necessity for standardized protocols and further research to validate multimodal therapy in recurrent CBTs.
ISSN:2730-6011