Characteristics, incidence trends, and treatment outcomes of tuberculosis patients with diabetes in Chongqing city from 2016 to 2022: an analysis of registration data
ObjectiveTo understand the epidemiologic trends and factors influencing the prevention and control of pulmonary tuberculosis with diabetes mellitus (PTB-DM) in Chongqing city, and to provide a basis for reducing the risk of comorbidities and improving patient outcomes in the region. MethodsData on P...
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Editorial Office of Chinese Journal of Public Health
2025-01-01
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| Series: | Zhongguo gonggong weisheng |
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| Online Access: | https://www.zgggws.com/article/doi/10.11847/zgggws1144768 |
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| author | Deliang KONG Yichao SHUI Xiangliu WANG Ting ZHANG Chengguo WU Mo HAO Chengyue LI Jiyuan ZHONG Chuan PU |
| author_facet | Deliang KONG Yichao SHUI Xiangliu WANG Ting ZHANG Chengguo WU Mo HAO Chengyue LI Jiyuan ZHONG Chuan PU |
| author_sort | Deliang KONG |
| collection | DOAJ |
| description | ObjectiveTo understand the epidemiologic trends and factors influencing the prevention and control of pulmonary tuberculosis with diabetes mellitus (PTB-DM) in Chongqing city, and to provide a basis for reducing the risk of comorbidities and improving patient outcomes in the region. MethodsData on PTB-DM patients registered in Chongqing city from 2016 to 2022 were extracted from the National Tuberculosis Information Management System. Descriptive analysis was used to analyze disease trends and demographic characteristics. Chi-square test was used to compare between groups. Multivariate unconditional logistic regression was used to analyze factors influencing patient outcomes. Joinpoint regression model was used to analyze disease trends. ResultsFrom 2016 to 2022, the average registration rate of PTB patients in Chongqing city was 49.38/100 000, with a decreasing trend (average annual percentage change [AAPC]= −10.70%, 95% confidence interval [95%CI]: 16.16%–5.63%). The average registration rate of PTB-DM patients was 2.9/100 000, with an increasing trend (AAPC=14.38%, 95%CI: 7.08%–23.73%). Enrolled PTB-DM were predominantly male, older, referred, had delayed medical visits, and had positive pathogen detection results. Among the outcomes of PTB-DM patients, successful treatment accounted for 80.85% and adverse outcomes accounted for 19.15%. The average annual treatment success rate was 82.01%. Joinpoint regression analysis showed a decreasing trend in the patients′ treatment success rate. Multivariate unconditional logistic regression analysis showed that ethnic minorities (odds ratio [OR]=0.744, 95%CI: 0.633–0.874), 0–24 years old (OR=0.217, 95%CI: 0.051–0.922), 25–39 years old (OR=0.540, 95%CI: 0.398–0.734), 40–54 years old (OR=0.488, 95%CI: 0.416–0.572), 55–64 years old (OR=0.709, 95%CI: 0.607–0.828), initial treatment (OR=0.648, 95%CI: 0.531–0.791), and with negative pathogen detection results (OR=0.576, 95%CI: 0.489–0.677) were protective factors against adverse outcomes in PTB-DM patients. Living in southeast Chongqing (OR=1.560, 95%CI: 1.218–1.999) and being referred for treatment (OR=1.289, 95%CI: 1.080–1.539) were risk factors for adverse outcomes in PTB-DM patients. ConclusionsThe co-morbidity trend of PTB-DM in Chongqing city is obvious. Treatment and management factors, such as diagnostic route, delayed medical visits and management methods, have an impact on the treatment outcomes of PTB-DM patients. |
| format | Article |
| id | doaj-art-1ae95d4a43d843488cc4fbbff63efb60 |
| institution | DOAJ |
| issn | 1001-0580 |
| language | zho |
| publishDate | 2025-01-01 |
| publisher | Editorial Office of Chinese Journal of Public Health |
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| series | Zhongguo gonggong weisheng |
| spelling | doaj-art-1ae95d4a43d843488cc4fbbff63efb602025-08-20T02:56:45ZzhoEditorial Office of Chinese Journal of Public HealthZhongguo gonggong weisheng1001-05802025-01-01411808710.11847/zgggws11447681144768Characteristics, incidence trends, and treatment outcomes of tuberculosis patients with diabetes in Chongqing city from 2016 to 2022: an analysis of registration dataDeliang KONG0Yichao SHUI1Xiangliu WANG2Ting ZHANG3Chengguo WU4Mo HAO5Chengyue LI6Jiyuan ZHONG7Chuan PU8Center for Medicine and Social Development, School of Public Health, Chongqing Medical University, Chongqing 400016, ChinaCenter for Medicine and Social Development, School of Public Health, Chongqing Medical University, Chongqing 400016, ChinaCenter for Medicine and Social Development, School of Public Health, Chongqing Medical University, Chongqing 400016, ChinaChongqing Tuberculosis Control Institute, Chongqing 400050, ChinaChongqing Tuberculosis Control Institute, Chongqing 400050, ChinaFudan University Center for Health Development and Strategy Studies, Shanghai 200032, ChinaFudan University Center for Health Development and Strategy Studies, Shanghai 200032, ChinaChongqing Tuberculosis Control Institute, Chongqing 400050, ChinaCenter for Medicine and Social Development, School of Public Health, Chongqing Medical University, Chongqing 400016, ChinaObjectiveTo understand the epidemiologic trends and factors influencing the prevention and control of pulmonary tuberculosis with diabetes mellitus (PTB-DM) in Chongqing city, and to provide a basis for reducing the risk of comorbidities and improving patient outcomes in the region. MethodsData on PTB-DM patients registered in Chongqing city from 2016 to 2022 were extracted from the National Tuberculosis Information Management System. Descriptive analysis was used to analyze disease trends and demographic characteristics. Chi-square test was used to compare between groups. Multivariate unconditional logistic regression was used to analyze factors influencing patient outcomes. Joinpoint regression model was used to analyze disease trends. ResultsFrom 2016 to 2022, the average registration rate of PTB patients in Chongqing city was 49.38/100 000, with a decreasing trend (average annual percentage change [AAPC]= −10.70%, 95% confidence interval [95%CI]: 16.16%–5.63%). The average registration rate of PTB-DM patients was 2.9/100 000, with an increasing trend (AAPC=14.38%, 95%CI: 7.08%–23.73%). Enrolled PTB-DM were predominantly male, older, referred, had delayed medical visits, and had positive pathogen detection results. Among the outcomes of PTB-DM patients, successful treatment accounted for 80.85% and adverse outcomes accounted for 19.15%. The average annual treatment success rate was 82.01%. Joinpoint regression analysis showed a decreasing trend in the patients′ treatment success rate. Multivariate unconditional logistic regression analysis showed that ethnic minorities (odds ratio [OR]=0.744, 95%CI: 0.633–0.874), 0–24 years old (OR=0.217, 95%CI: 0.051–0.922), 25–39 years old (OR=0.540, 95%CI: 0.398–0.734), 40–54 years old (OR=0.488, 95%CI: 0.416–0.572), 55–64 years old (OR=0.709, 95%CI: 0.607–0.828), initial treatment (OR=0.648, 95%CI: 0.531–0.791), and with negative pathogen detection results (OR=0.576, 95%CI: 0.489–0.677) were protective factors against adverse outcomes in PTB-DM patients. Living in southeast Chongqing (OR=1.560, 95%CI: 1.218–1.999) and being referred for treatment (OR=1.289, 95%CI: 1.080–1.539) were risk factors for adverse outcomes in PTB-DM patients. ConclusionsThe co-morbidity trend of PTB-DM in Chongqing city is obvious. Treatment and management factors, such as diagnostic route, delayed medical visits and management methods, have an impact on the treatment outcomes of PTB-DM patients.https://www.zgggws.com/article/doi/10.11847/zgggws1144768tuberculosisdiabetescomorbidityepidemiological trendtreatment outcomechongqing city |
| spellingShingle | Deliang KONG Yichao SHUI Xiangliu WANG Ting ZHANG Chengguo WU Mo HAO Chengyue LI Jiyuan ZHONG Chuan PU Characteristics, incidence trends, and treatment outcomes of tuberculosis patients with diabetes in Chongqing city from 2016 to 2022: an analysis of registration data Zhongguo gonggong weisheng tuberculosis diabetes comorbidity epidemiological trend treatment outcome chongqing city |
| title | Characteristics, incidence trends, and treatment outcomes of tuberculosis patients with diabetes in Chongqing city from 2016 to 2022: an analysis of registration data |
| title_full | Characteristics, incidence trends, and treatment outcomes of tuberculosis patients with diabetes in Chongqing city from 2016 to 2022: an analysis of registration data |
| title_fullStr | Characteristics, incidence trends, and treatment outcomes of tuberculosis patients with diabetes in Chongqing city from 2016 to 2022: an analysis of registration data |
| title_full_unstemmed | Characteristics, incidence trends, and treatment outcomes of tuberculosis patients with diabetes in Chongqing city from 2016 to 2022: an analysis of registration data |
| title_short | Characteristics, incidence trends, and treatment outcomes of tuberculosis patients with diabetes in Chongqing city from 2016 to 2022: an analysis of registration data |
| title_sort | characteristics incidence trends and treatment outcomes of tuberculosis patients with diabetes in chongqing city from 2016 to 2022 an analysis of registration data |
| topic | tuberculosis diabetes comorbidity epidemiological trend treatment outcome chongqing city |
| url | https://www.zgggws.com/article/doi/10.11847/zgggws1144768 |
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