Long-term survival in advanced pulmonary large-cell neuroendocrine carcinoma after multi-line immunochemotherapy and anti-angiogenic therapy: a case report

Long-term survival in advanced pulmonary large-cell neuroendocrine carcinoma after multi-line immunochemotherapy and anti-angiogenic therapy: a case report

BackgroundPulmonary large-cell neuroendocrine carcinoma (PLCNEC) is a rare and highly aggressive subtype of lung cancer with neuroendocrine features, typically diagnosed at an advanced stage. Its clinical presentation and treatment response resemble those of small cell lung cancer, whereas its histo...

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Bibliographic Details
Main Authors:	Hongming Wang, Shiyan Li, Xiaoyang Liu, Yan Zhang, Jiang Zheng, Yangfeng Du, Zemin Xiao, Nuoni Wang, Zhijun Wu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Immunology
Subjects:	immunochemotherapy anti-angiogenic therapy survival pulmonary large-cell neuroendocrine carcinoma case report
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1618672/full
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