Effect of initiation of antiretroviral drugs for HIV prevention or treatment on the vaginal microbiome of pregnant women in Malawi

Effect of initiation of antiretroviral drugs for HIV prevention or treatment on the vaginal microbiome of pregnant women in Malawi

Abstract Lack of Lactobacillus and/or dysbiosis is linked to spontaneous preterm birth (sPTB). The impact of antiretrovirals (ARVs) for HIV treatment or prevention on the vaginal microbiome during pregnancy remains unclear. We examined vaginal microbiome changes in pregnant women in Lilongwe, Malawi...

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Main Authors: Friday Saidi, Lauren A. Graybill, Jennifer H. Tang, Twambilile Phanga, Beteniko Milala, Gabriel Banda, Manley Kamija, Margaret Kasaro, Wilbroad Mutale, Joan Price, Lameck Chinula, Jeffrey Stringer, Mina C. Hosseinipour, Benjamin H. Chi, Jacques Ravel, Johanna B. Holm
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-025-00697-8
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