Implantable Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction: A Single-Institution Retrospective Study

Purpose Neurogenic lower urinary tract dysfunction (NLUTD) is highly prevalent among patients with neurologic disorders. Some studies have demonstrated that implantable neuromodulation can improve symptoms of NLUTD. We seek to describe our experience with sacral and pudendal neuromodulation in patie...

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Main Authors: Karis Buford, Haley Eisner, Annah Vollstedt, Brett Friedman, Jason Gilleran, Bernadette M.M. Zwaans, Kenneth M. Peters, Priya Padmanabhan
Format: Article
Language:English
Published: Korean Continence Society 2024-12-01
Series:International Neurourology Journal
Subjects:
Online Access:http://einj.org/upload/pdf/inj-2448144-122.pdf
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author Karis Buford
Haley Eisner
Annah Vollstedt
Brett Friedman
Jason Gilleran
Bernadette M.M. Zwaans
Kenneth M. Peters
Priya Padmanabhan
author_facet Karis Buford
Haley Eisner
Annah Vollstedt
Brett Friedman
Jason Gilleran
Bernadette M.M. Zwaans
Kenneth M. Peters
Priya Padmanabhan
author_sort Karis Buford
collection DOAJ
description Purpose Neurogenic lower urinary tract dysfunction (NLUTD) is highly prevalent among patients with neurologic disorders. Some studies have demonstrated that implantable neuromodulation can improve symptoms of NLUTD. We seek to describe our experience with sacral and pudendal neuromodulation in patients with NLUTD. Methods A retrospective chart review of patients with “neurogenic bladder” ICD-9/10 (International Classification of Diseases, Ninth Revision/10th Revision) code was performed at a single institution. This included patients from 2008 to 2020 who underwent stage 1 neuromodulation trial. Demographic and clinical information was collected, including neurologic diagnosis, the character of patients’ voiding symptoms, the presence or absence of fecal incontinence, the need for intermittent catheterization, and whether patients had sufficient (>50%) improvement in their symptoms to undergo stage 2 implantable pulse generator (IPG) placement. Results We identified 82 patients with neurologic diagnoses who underwent stage 1 neuromodulation. The most common diagnoses were diabetic cystopathy (17.07%), spinal surgery (17.07%), and spinal cord injury (12.20%). The most commonly reported symptoms were urinary urgency, and urge urinary incontinence. Overall, 59 patients (71.95%) advanced to stage 2 IPG placement including 72% of patients with sacral leads and 76% with pudendal leads. Conclusions Neuromodulation is feasible and effective in the treatment of NLUTD. Further investigation into its utilization is warranted.
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2093-6931
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spelling doaj-art-1ad42976c4dc429a98b844baff0eb0ae2025-08-20T03:41:59ZengKorean Continence SocietyInternational Neurourology Journal2093-47772093-69312024-12-0128427828410.5213/inj.2448144.1221138Implantable Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction: A Single-Institution Retrospective StudyKaris Buford0Haley Eisner1Annah Vollstedt2Brett Friedman3Jason Gilleran4Bernadette M.M. Zwaans5Kenneth M. Peters6Priya Padmanabhan7 Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA University of Iowa, Iowa City, IA, USA Oakland University William Beaumont School of Medicine, Rochester, MI, USA Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA Corewell Health William Beaumont University Hospital, Royal Oak, MI, USAPurpose Neurogenic lower urinary tract dysfunction (NLUTD) is highly prevalent among patients with neurologic disorders. Some studies have demonstrated that implantable neuromodulation can improve symptoms of NLUTD. We seek to describe our experience with sacral and pudendal neuromodulation in patients with NLUTD. Methods A retrospective chart review of patients with “neurogenic bladder” ICD-9/10 (International Classification of Diseases, Ninth Revision/10th Revision) code was performed at a single institution. This included patients from 2008 to 2020 who underwent stage 1 neuromodulation trial. Demographic and clinical information was collected, including neurologic diagnosis, the character of patients’ voiding symptoms, the presence or absence of fecal incontinence, the need for intermittent catheterization, and whether patients had sufficient (>50%) improvement in their symptoms to undergo stage 2 implantable pulse generator (IPG) placement. Results We identified 82 patients with neurologic diagnoses who underwent stage 1 neuromodulation. The most common diagnoses were diabetic cystopathy (17.07%), spinal surgery (17.07%), and spinal cord injury (12.20%). The most commonly reported symptoms were urinary urgency, and urge urinary incontinence. Overall, 59 patients (71.95%) advanced to stage 2 IPG placement including 72% of patients with sacral leads and 76% with pudendal leads. Conclusions Neuromodulation is feasible and effective in the treatment of NLUTD. Further investigation into its utilization is warranted.http://einj.org/upload/pdf/inj-2448144-122.pdfneuromodulationneurogenic lower urinary tract dysfunctionneurogenic bladderspina bifida
spellingShingle Karis Buford
Haley Eisner
Annah Vollstedt
Brett Friedman
Jason Gilleran
Bernadette M.M. Zwaans
Kenneth M. Peters
Priya Padmanabhan
Implantable Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction: A Single-Institution Retrospective Study
International Neurourology Journal
neuromodulation
neurogenic lower urinary tract dysfunction
neurogenic bladder
spina bifida
title Implantable Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction: A Single-Institution Retrospective Study
title_full Implantable Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction: A Single-Institution Retrospective Study
title_fullStr Implantable Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction: A Single-Institution Retrospective Study
title_full_unstemmed Implantable Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction: A Single-Institution Retrospective Study
title_short Implantable Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction: A Single-Institution Retrospective Study
title_sort implantable neuromodulation for neurogenic lower urinary tract dysfunction a single institution retrospective study
topic neuromodulation
neurogenic lower urinary tract dysfunction
neurogenic bladder
spina bifida
url http://einj.org/upload/pdf/inj-2448144-122.pdf
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