Intestinal metabolite homocysteine participates in the regulation of irritable bowel syndrome

Intestinal metabolite homocysteine participates in the regulation of irritable bowel syndrome

Objective To investigate the role of homocysteine (Hcy) in the pathogenesis of irritable bowel syndrome (IBS) and its effects on intestinal motility, visceral hypersensitivity, and barrier function. Methods Clinical cohorts and animal models were combined for this study. Clinically, fifteen IBS pati...

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Bibliographic Details
Main Author: LU Shaochong, YE Haozhen, HOU Songyuan, ZHOU Yesheng, LIU Si, ZHU Shengtao
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2025-07-01
Series:Jichu yixue yu linchuang
Subjects:
irritable bowel syndrome|homocysteine|intestinal barrier function|visceral hypersensitivity|tight junction protein
Online Access:https://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2025-45-7-858.pdf
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