Opportunities and Challenges in Early-Stage TB Drug Discovery: Targeting DNA Replication as a Case Study

The TB drug pipeline has begun to deliver new and repurposed drugs and combinations which have revolutionized the treatment of drug-resistant TB and shown that treatment-shortening is an achievable goal. Maintaining this momentum requires replenishment of the pipeline with high-quality ‘hit’ compoun...

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Bibliographic Details
Main Authors: Prof Valerie Mizrahi, Melissa Chengalroyen, Sasha Lynch, Mandy Mason
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971225000396
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