FpnA, the Aspergillus fumigatus homolog of human ferroportin, mediates resistance to nickel, cobalt and gallium but does not function in iron homeostasis

Abstract Iron homeostasis is key to both the survival of virtually all organisms and the virulence of fungi including Aspergillus fumigatus, a human fungal pathogen causing life-threatening invasive infections. Unlike the extensively studied fungal species Saccharomyces cerevisiae and Schizosaccharo...

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Main Authors: Isidor Happacher, Simon Oberegger, Beate Abt, Annie Yap, Patricia Caballero, Mario Aguiar, Javeria Pervaiz, Giacomo Gariglio, Matthias Misslinger, Clemens Decristoforo, Hubertus Haas
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07799-1
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