Nonclinical evaluation of HBG1/2 and BCL11A as genome-editing targets for the treatment of β-hemoglobinopathies

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Main Authors: Tusneem Janoudi, Mrunali Jagdale, Meng Wu, Sanjana Gorlla, Peisheng Zhang, Ying Shao, Li Li, Sheryl R. Bowley, Eugenio Marco, Kai-Hsin Chang
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952924007055
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author Tusneem Janoudi
Mrunali Jagdale
Meng Wu
Sanjana Gorlla
Peisheng Zhang
Ying Shao
Li Li
Sheryl R. Bowley
Eugenio Marco
Kai-Hsin Chang
author_facet Tusneem Janoudi
Mrunali Jagdale
Meng Wu
Sanjana Gorlla
Peisheng Zhang
Ying Shao
Li Li
Sheryl R. Bowley
Eugenio Marco
Kai-Hsin Chang
author_sort Tusneem Janoudi
collection DOAJ
format Article
id doaj-art-1abca2bbe45e4c8a80955300dae87c1a
institution DOAJ
issn 2473-9529
language English
publishDate 2025-02-01
publisher Elsevier
record_format Article
series Blood Advances
spelling doaj-art-1abca2bbe45e4c8a80955300dae87c1a2025-08-20T03:11:37ZengElsevierBlood Advances2473-95292025-02-019480881310.1182/bloodadvances.2024014040Nonclinical evaluation of HBG1/2 and BCL11A as genome-editing targets for the treatment of β-hemoglobinopathiesTusneem Janoudi0Mrunali Jagdale1Meng Wu2Sanjana Gorlla3Peisheng Zhang4Ying Shao5Li Li6Sheryl R. Bowley7Eugenio Marco8Kai-Hsin Chang9Editas Medicine Inc, Cambridge, MAEditas Medicine Inc, Cambridge, MAEditas Medicine Inc, Cambridge, MAEditas Medicine Inc, Cambridge, MAEditas Medicine Inc, Cambridge, MAEditas Medicine Inc, Cambridge, MAEditas Medicine Inc, Cambridge, MAEditas Medicine Inc, Cambridge, MAEditas Medicine Inc, Cambridge, MAEditas Medicine Inc, Cambridge, MA; Correspondence: Kai-Hsin Chang, Editas Medicine Inc, 11 Hurley St, Cambridge, MA 02141;http://www.sciencedirect.com/science/article/pii/S2473952924007055
spellingShingle Tusneem Janoudi
Mrunali Jagdale
Meng Wu
Sanjana Gorlla
Peisheng Zhang
Ying Shao
Li Li
Sheryl R. Bowley
Eugenio Marco
Kai-Hsin Chang
Nonclinical evaluation of HBG1/2 and BCL11A as genome-editing targets for the treatment of β-hemoglobinopathies
Blood Advances
title Nonclinical evaluation of HBG1/2 and BCL11A as genome-editing targets for the treatment of β-hemoglobinopathies
title_full Nonclinical evaluation of HBG1/2 and BCL11A as genome-editing targets for the treatment of β-hemoglobinopathies
title_fullStr Nonclinical evaluation of HBG1/2 and BCL11A as genome-editing targets for the treatment of β-hemoglobinopathies
title_full_unstemmed Nonclinical evaluation of HBG1/2 and BCL11A as genome-editing targets for the treatment of β-hemoglobinopathies
title_short Nonclinical evaluation of HBG1/2 and BCL11A as genome-editing targets for the treatment of β-hemoglobinopathies
title_sort nonclinical evaluation of hbg1 2 and bcl11a as genome editing targets for the treatment of β hemoglobinopathies
url http://www.sciencedirect.com/science/article/pii/S2473952924007055
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