Antimetastatic Therapies of the Polysulfide Diallyl Trisulfide against Triple-Negative Breast Cancer (TNBC) via Suppressing MMP2/9 by Blocking NF-κB and ERK/MAPK Signaling Pathways.

Antimetastatic Therapies of the Polysulfide Diallyl Trisulfide against Triple-Negative Breast Cancer (TNBC) via Suppressing MMP2/9 by Blocking NF-κB and ERK/MAPK Signaling Pathways.

<h4>Background</h4>Migration and invasion are two crucial steps of tumor metastasis. Blockage of these steps may be an effective strategy to reduce the risk. The objective of the present study was to investigate the effects of diallyl trisulfide (DATS), a natural organosulfuric compound...

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Main Authors: Yuping Liu, Pingting Zhu, Yingyu Wang, Zhonghong Wei, Li Tao, Zhijie Zhu, Xiaobo Sheng, Siliang Wang, Junshan Ruan, Zhaoguo Liu, Yuzhu Cao, Yunlong Shan, Lihua Sun, Aiyun Wang, Wenxing Chen, Yin Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0123781&type=printable
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