Schwannoma of the Appendix Orifice

Schwannomas are rare mesenchymal tumors. They are usually diagnosed incidentally during endoscopic or diagnostic imaging for another reason. Malignant transformation is rare. In this case report, we present an incidental schwannoma protruding through the appendiceal orifice diagnosed during endoscop...

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Main Authors: Maha Alkhattab, Amenah Dhannoon, Rishabh Sehgal, Conor Gormley, Margaret Sheehan, Ray Mclaughlin
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2021/7250145
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author Maha Alkhattab
Amenah Dhannoon
Rishabh Sehgal
Conor Gormley
Margaret Sheehan
Ray Mclaughlin
author_facet Maha Alkhattab
Amenah Dhannoon
Rishabh Sehgal
Conor Gormley
Margaret Sheehan
Ray Mclaughlin
author_sort Maha Alkhattab
collection DOAJ
description Schwannomas are rare mesenchymal tumors. They are usually diagnosed incidentally during endoscopic or diagnostic imaging for another reason. Malignant transformation is rare. In this case report, we present an incidental schwannoma protruding through the appendiceal orifice diagnosed during endoscopy. A healthy 56-year-old female underwent a surveillance colonoscopy for family history of colorectal cancer. A prominent and edematous appendiceal orifice was noted, and the area was aggressively biopsied. Histopathological assessment revealed a benign schwannoma. Computerized topography was unremarkable. Subsequently, the patient underwent a right hemicolectomy. Patient is scheduled to undergo routine surveillance in three years. Grossly, schwannomas are white, encapsulated, and well-circumscribed lesions that stain strongly positive for S100, GFAP, and CD57. Histologically, schwannomas demonstrate spindle cell proliferation. Several imaging modalities have been utilized in the diagnosis and management of mesenchymal neoplasms. Despite the benign nature of the diagnosis, complete surgical resection with clear margins remains the gold standard management strategy. Our case highlights the presence of a relatively uncommon tumor in an unusual anatomical location.
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spelling doaj-art-1ab34fd135b145a7b1e0ce6948dd99be2025-08-20T02:02:20ZengWileyCase Reports in Pathology2090-679X2021-01-01202110.1155/2021/7250145Schwannoma of the Appendix OrificeMaha Alkhattab0Amenah Dhannoon1Rishabh Sehgal2Conor Gormley3Margaret Sheehan4Ray Mclaughlin5Department of SurgeryDepartment of SurgeryDepartment of SurgeryDepartment of AnesthesiologyDepartment of PathologyDepartment of SurgerySchwannomas are rare mesenchymal tumors. They are usually diagnosed incidentally during endoscopic or diagnostic imaging for another reason. Malignant transformation is rare. In this case report, we present an incidental schwannoma protruding through the appendiceal orifice diagnosed during endoscopy. A healthy 56-year-old female underwent a surveillance colonoscopy for family history of colorectal cancer. A prominent and edematous appendiceal orifice was noted, and the area was aggressively biopsied. Histopathological assessment revealed a benign schwannoma. Computerized topography was unremarkable. Subsequently, the patient underwent a right hemicolectomy. Patient is scheduled to undergo routine surveillance in three years. Grossly, schwannomas are white, encapsulated, and well-circumscribed lesions that stain strongly positive for S100, GFAP, and CD57. Histologically, schwannomas demonstrate spindle cell proliferation. Several imaging modalities have been utilized in the diagnosis and management of mesenchymal neoplasms. Despite the benign nature of the diagnosis, complete surgical resection with clear margins remains the gold standard management strategy. Our case highlights the presence of a relatively uncommon tumor in an unusual anatomical location.http://dx.doi.org/10.1155/2021/7250145
spellingShingle Maha Alkhattab
Amenah Dhannoon
Rishabh Sehgal
Conor Gormley
Margaret Sheehan
Ray Mclaughlin
Schwannoma of the Appendix Orifice
Case Reports in Pathology
title Schwannoma of the Appendix Orifice
title_full Schwannoma of the Appendix Orifice
title_fullStr Schwannoma of the Appendix Orifice
title_full_unstemmed Schwannoma of the Appendix Orifice
title_short Schwannoma of the Appendix Orifice
title_sort schwannoma of the appendix orifice
url http://dx.doi.org/10.1155/2021/7250145
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