Nucleolar ribosomal RNA synthesis continues in differentiating lens fiber cells until abrupt nuclear degradation required for ocular lens transparency

Nucleolar ribosomal RNA synthesis continues in differentiating lens fiber cells until abrupt nuclear degradation required for ocular lens transparency

Cellular differentiation requires highly coordinated action of all three transcriptional systems to produce rRNAs, mRNAs and various ‘short’ and ‘long’ non-coding RNAs by RNA Polymerase I, II and III systems, respectively. RNA Polymerase I catalyzes transcription of about 400 copies of mammalian rDN...

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Bibliographic Details
Main Authors: Danielle Rayêe, U. Thomas Meier, Carolina Eliscovich, Aleš Cvekl
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:RNA Biology
Subjects:
Lens
nucleus
nucleoli
organelle-free zone
rRNA transcription
RNA polymerase I
Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2025.2483118
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