Optogenetic Control of the Mitochondrial Protein Import in Mammalian Cells

Optogenetic Control of the Mitochondrial Protein Import in Mammalian Cells

Mitochondria provide cells with energy and regulate the cellular metabolism. Almost all mitochondrial proteins are nuclear-encoded, translated on ribosomes in the cytoplasm, and subsequently transferred to the different subcellular compartments of mitochondria. Here, we developed OptoMitoImport, an...

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Bibliographic Details
Main Authors: Lukas F. J. Althoff, Markus M. Kramer, Benjamin Bührer, Denise Gaspar, Gerald Radziwill
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Cells
Subjects:
optogenetics
mitochondrial import
matrix peptidases
CRY2
LOV domain
MTS
Online Access:https://www.mdpi.com/2073-4409/13/19/1671
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