Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications
Adipose-derived stem cells (ASCs) are a mesenchymal stem cell source with properties of self-renewal and multipotential differentiation. Compared to bone marrow-derived stem cells (BMSCs), ASCs can be derived from more sources and are harvested more easily. Three-dimensional (3D) tissue engineering...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2016/6737345 |
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| _version_ | 1832547487265587200 |
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| author | Ru Dai Zongjie Wang Roya Samanipour Kyo-in Koo Keekyoung Kim |
| author_facet | Ru Dai Zongjie Wang Roya Samanipour Kyo-in Koo Keekyoung Kim |
| author_sort | Ru Dai |
| collection | DOAJ |
| description | Adipose-derived stem cells (ASCs) are a mesenchymal stem cell source with properties of self-renewal and multipotential differentiation. Compared to bone marrow-derived stem cells (BMSCs), ASCs can be derived from more sources and are harvested more easily. Three-dimensional (3D) tissue engineering scaffolds are better able to mimic the in vivo cellular microenvironment, which benefits the localization, attachment, proliferation, and differentiation of ASCs. Therefore, tissue-engineered ASCs are recognized as an attractive substitute for tissue and organ transplantation. In this paper, we review the characteristics of ASCs, as well as the biomaterials and tissue engineering methods used to proliferate and differentiate ASCs in a 3D environment. Clinical applications of tissue-engineered ASCs are also discussed to reveal the potential and feasibility of using tissue-engineered ASCs in regenerative medicine. |
| format | Article |
| id | doaj-art-1a9fb0cda8654dd68c3966c084354265 |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-1a9fb0cda8654dd68c3966c0843542652025-02-03T06:44:34ZengWileyStem Cells International1687-966X1687-96782016-01-01201610.1155/2016/67373456737345Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine ApplicationsRu Dai0Zongjie Wang1Roya Samanipour2Kyo-in Koo3Keekyoung Kim4School of Engineering, University of British Columbia, Kelowna, BC, V1V 1V7, CanadaSchool of Engineering, University of British Columbia, Kelowna, BC, V1V 1V7, CanadaSchool of Engineering, University of British Columbia, Kelowna, BC, V1V 1V7, CanadaDepartment of Biomedical Engineering, University of Ulsan, Ulsan 680-749, Republic of KoreaSchool of Engineering, University of British Columbia, Kelowna, BC, V1V 1V7, CanadaAdipose-derived stem cells (ASCs) are a mesenchymal stem cell source with properties of self-renewal and multipotential differentiation. Compared to bone marrow-derived stem cells (BMSCs), ASCs can be derived from more sources and are harvested more easily. Three-dimensional (3D) tissue engineering scaffolds are better able to mimic the in vivo cellular microenvironment, which benefits the localization, attachment, proliferation, and differentiation of ASCs. Therefore, tissue-engineered ASCs are recognized as an attractive substitute for tissue and organ transplantation. In this paper, we review the characteristics of ASCs, as well as the biomaterials and tissue engineering methods used to proliferate and differentiate ASCs in a 3D environment. Clinical applications of tissue-engineered ASCs are also discussed to reveal the potential and feasibility of using tissue-engineered ASCs in regenerative medicine.http://dx.doi.org/10.1155/2016/6737345 |
| spellingShingle | Ru Dai Zongjie Wang Roya Samanipour Kyo-in Koo Keekyoung Kim Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications Stem Cells International |
| title | Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications |
| title_full | Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications |
| title_fullStr | Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications |
| title_full_unstemmed | Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications |
| title_short | Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications |
| title_sort | adipose derived stem cells for tissue engineering and regenerative medicine applications |
| url | http://dx.doi.org/10.1155/2016/6737345 |
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