BONE MARROW INVOLVEMENT IN A PATIENT WITH ALPHA HEAVYCHAIN DISEASE:RESPONSE TO TETRACYCLINE TREATMENT
A 28-year-old man from East Mediterranean admitted with abdominal pain, weight loss and diarrhea. Barium x-ray studies showed segmentation, dilatation of bowel loops, mucosal folds thickening and delayed intestinal transit. Histological examination of biopsy specimens revealed villous atrophy and pl...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2014-08-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | https://mjhid.org/index.php/mjhid/article/view/1833 |
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| author | Zahit Bolaman Irfan Yavasoglu Gokhan Sargin Gurhan Kadikoylu Firuzan Kacar Doger |
| author_facet | Zahit Bolaman Irfan Yavasoglu Gokhan Sargin Gurhan Kadikoylu Firuzan Kacar Doger |
| author_sort | Zahit Bolaman |
| collection | DOAJ |
| description | A 28-year-old man from East Mediterranean admitted with abdominal pain, weight loss and diarrhea. Barium x-ray studies showed segmentation, dilatation of bowel loops, mucosal folds thickening and delayed intestinal transit. Histological examination of biopsy specimens revealed villous atrophy and plasmacytic infiltration limited to mucosa and submucosa. Computed tomography showed multiple lymphadenopathy in the abdomen. Serum protein electropheresis and immunoelectropheresis indicated elevated IgA concentration. Bone marrow aspiration and biopsy revealed presence of lymphoplasmacytic infiltration. Immunohistochemical analysis of the intestine, lymph nodes showed positivity for CD45, CD-79, CD-20. After tetracycline treatment the patient’s symptoms, abdominal lymphadenopathy and bone marrow infiltration disappeared and IgA concentration decreased to normal levels. |
| format | Article |
| id | doaj-art-1a9f4f94a8094c5d966dfd420258369f |
| institution | OA Journals |
| issn | 2035-3006 |
| language | English |
| publishDate | 2014-08-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-1a9f4f94a8094c5d966dfd420258369f2025-08-20T01:47:47ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-08-011BONE MARROW INVOLVEMENT IN A PATIENT WITH ALPHA HEAVYCHAIN DISEASE:RESPONSE TO TETRACYCLINE TREATMENTZahit Bolaman0Irfan Yavasoglu1Gokhan Sargin2Gurhan Kadikoylu3Firuzan Kacar Doger4Adnan Menderes University Medical Faculty, Division of HematologyAdnan Menderes University Medical Faculty, Division of HematologyAdnan Menderes University Medical Faculty, Division of HematologyAdnan Menderes University Medical Faculty, Division of HematologyAdnan Menderes University Faculty of Medicine, Department of PathologyA 28-year-old man from East Mediterranean admitted with abdominal pain, weight loss and diarrhea. Barium x-ray studies showed segmentation, dilatation of bowel loops, mucosal folds thickening and delayed intestinal transit. Histological examination of biopsy specimens revealed villous atrophy and plasmacytic infiltration limited to mucosa and submucosa. Computed tomography showed multiple lymphadenopathy in the abdomen. Serum protein electropheresis and immunoelectropheresis indicated elevated IgA concentration. Bone marrow aspiration and biopsy revealed presence of lymphoplasmacytic infiltration. Immunohistochemical analysis of the intestine, lymph nodes showed positivity for CD45, CD-79, CD-20. After tetracycline treatment the patient’s symptoms, abdominal lymphadenopathy and bone marrow infiltration disappeared and IgA concentration decreased to normal levels.https://mjhid.org/index.php/mjhid/article/view/1833alpha heavy chainIPSIDMediterranean lymphomatetracycline |
| spellingShingle | Zahit Bolaman Irfan Yavasoglu Gokhan Sargin Gurhan Kadikoylu Firuzan Kacar Doger BONE MARROW INVOLVEMENT IN A PATIENT WITH ALPHA HEAVYCHAIN DISEASE:RESPONSE TO TETRACYCLINE TREATMENT Mediterranean Journal of Hematology and Infectious Diseases alpha heavy chain IPSID Mediterranean lymphoma tetracycline |
| title | BONE MARROW INVOLVEMENT IN A PATIENT WITH ALPHA HEAVYCHAIN DISEASE:RESPONSE TO TETRACYCLINE TREATMENT |
| title_full | BONE MARROW INVOLVEMENT IN A PATIENT WITH ALPHA HEAVYCHAIN DISEASE:RESPONSE TO TETRACYCLINE TREATMENT |
| title_fullStr | BONE MARROW INVOLVEMENT IN A PATIENT WITH ALPHA HEAVYCHAIN DISEASE:RESPONSE TO TETRACYCLINE TREATMENT |
| title_full_unstemmed | BONE MARROW INVOLVEMENT IN A PATIENT WITH ALPHA HEAVYCHAIN DISEASE:RESPONSE TO TETRACYCLINE TREATMENT |
| title_short | BONE MARROW INVOLVEMENT IN A PATIENT WITH ALPHA HEAVYCHAIN DISEASE:RESPONSE TO TETRACYCLINE TREATMENT |
| title_sort | bone marrow involvement in a patient with alpha heavychain disease response to tetracycline treatment |
| topic | alpha heavy chain IPSID Mediterranean lymphoma tetracycline |
| url | https://mjhid.org/index.php/mjhid/article/view/1833 |
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