The effect of non-linear signal in classification problems using gene expression.

Those building predictive models from transcriptomic data are faced with two conflicting perspectives. The first, based on the inherent high dimensionality of biological systems, supposes that complex non-linear models such as neural networks will better match complex biological systems. The second,...

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Bibliographic Details
Main Authors: Benjamin J Heil, Jake Crawford, Casey S Greene
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-03-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010984&type=printable
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