PRIMARY HEMOSTATIC SYSTEM CONDITION IN MUCOVISCIDOSIS IN CHILDREN

The article presents results of a study of platelet hemostasis in children with mucoviscidosis. Motionless and viscous mucus  becomes infected with various pathogenic and opportunistic microbes in the setting of disturbed mucociliary clearance; when inflammation becomes chronic, endothelial dysfunct...

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Main Authors: O. B. Gordeeva, V. V. Botvinyeva, O. I. Simonova, L. S. Namazova-Baranova, Y. V. Gorinova, E. L. Korolkova, M. A. Soloshenko, A. K. Gevorkyan
Format: Article
Language:Russian
Published: Union of pediatricians of Russia 2014-01-01
Series:Педиатрическая фармакология
Subjects:
Online Access:https://www.pedpharma.ru/jour/article/view/143
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author O. B. Gordeeva
V. V. Botvinyeva
O. I. Simonova
L. S. Namazova-Baranova
Y. V. Gorinova
E. L. Korolkova
M. A. Soloshenko
A. K. Gevorkyan
author_facet O. B. Gordeeva
V. V. Botvinyeva
O. I. Simonova
L. S. Namazova-Baranova
Y. V. Gorinova
E. L. Korolkova
M. A. Soloshenko
A. K. Gevorkyan
author_sort O. B. Gordeeva
collection DOAJ
description The article presents results of a study of platelet hemostasis in children with mucoviscidosis. Motionless and viscous mucus  becomes infected with various pathogenic and opportunistic microbes in the setting of disturbed mucociliary clearance; when inflammation becomes chronic, endothelial dysfunction and platelet aggregation disorder may provoke development of bloodstream complications. Early diagnostics of pathologic changes in primary hemostasis is important for therapy and disease prognosis.
format Article
id doaj-art-1a7df0c05cee4dea86bb1b7f55abc610
institution DOAJ
issn 1727-5776
2500-3089
language Russian
publishDate 2014-01-01
publisher Union of pediatricians of Russia
record_format Article
series Педиатрическая фармакология
spelling doaj-art-1a7df0c05cee4dea86bb1b7f55abc6102025-08-20T02:54:33ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892014-01-01111666810.15690/pf.v11i1.899143PRIMARY HEMOSTATIC SYSTEM CONDITION IN MUCOVISCIDOSIS IN CHILDRENO. B. Gordeeva0V. V. Botvinyeva1O. I. Simonova2L. S. Namazova-Baranova3Y. V. Gorinova4E. L. Korolkova5M. A. Soloshenko6A. K. Gevorkyan7Scientific Center of Children’s Heal​thScientific Center of Childrens Health, Moscow, Russian FederationScientific Center of Childrens Health, Moscow, Russian FederationScientific Center of Childrens Health, Moscow, Russian Federation First Sechenov Moscow State Medical University of the Ministry of Health of the Russian Federation Pirogov Russian National Medical Research University, MoscowScientific Center of Childrens Health, Moscow, Russian FederationScientific Center of Childrens Health, Moscow, Russian FederationScientific Center of Childrens Health, Moscow, Russian FederationScientific Center of Childrens Health, Moscow, Russian FederationThe article presents results of a study of platelet hemostasis in children with mucoviscidosis. Motionless and viscous mucus  becomes infected with various pathogenic and opportunistic microbes in the setting of disturbed mucociliary clearance; when inflammation becomes chronic, endothelial dysfunction and platelet aggregation disorder may provoke development of bloodstream complications. Early diagnostics of pathologic changes in primary hemostasis is important for therapy and disease prognosis.https://www.pedpharma.ru/jour/article/view/143platelet aggregate functionmucoviscidosisinflammationhemostasischildren
spellingShingle O. B. Gordeeva
V. V. Botvinyeva
O. I. Simonova
L. S. Namazova-Baranova
Y. V. Gorinova
E. L. Korolkova
M. A. Soloshenko
A. K. Gevorkyan
PRIMARY HEMOSTATIC SYSTEM CONDITION IN MUCOVISCIDOSIS IN CHILDREN
Педиатрическая фармакология
platelet aggregate function
mucoviscidosis
inflammation
hemostasis
children
title PRIMARY HEMOSTATIC SYSTEM CONDITION IN MUCOVISCIDOSIS IN CHILDREN
title_full PRIMARY HEMOSTATIC SYSTEM CONDITION IN MUCOVISCIDOSIS IN CHILDREN
title_fullStr PRIMARY HEMOSTATIC SYSTEM CONDITION IN MUCOVISCIDOSIS IN CHILDREN
title_full_unstemmed PRIMARY HEMOSTATIC SYSTEM CONDITION IN MUCOVISCIDOSIS IN CHILDREN
title_short PRIMARY HEMOSTATIC SYSTEM CONDITION IN MUCOVISCIDOSIS IN CHILDREN
title_sort primary hemostatic system condition in mucoviscidosis in children
topic platelet aggregate function
mucoviscidosis
inflammation
hemostasis
children
url https://www.pedpharma.ru/jour/article/view/143
work_keys_str_mv AT obgordeeva primaryhemostaticsystemconditioninmucoviscidosisinchildren
AT vvbotvinyeva primaryhemostaticsystemconditioninmucoviscidosisinchildren
AT oisimonova primaryhemostaticsystemconditioninmucoviscidosisinchildren
AT lsnamazovabaranova primaryhemostaticsystemconditioninmucoviscidosisinchildren
AT yvgorinova primaryhemostaticsystemconditioninmucoviscidosisinchildren
AT elkorolkova primaryhemostaticsystemconditioninmucoviscidosisinchildren
AT masoloshenko primaryhemostaticsystemconditioninmucoviscidosisinchildren
AT akgevorkyan primaryhemostaticsystemconditioninmucoviscidosisinchildren