A Novel <i>Closo</i>-<i>Ortho</i>-Carborane-Based Glucosamine Derivative as a Promising Agent for Boron Neutron Capture Therapy

A Novel <i>Closo</i>-<i>Ortho</i>-Carborane-Based Glucosamine Derivative as a Promising Agent for Boron Neutron Capture Therapy

<b>Background:</b> Boron Neutron Capture Therapy (BNCT) is a promising cancer treatment that combines tumor-selective boron delivery agents with thermal neutrons to kill cancer cells while sparing normal tissue. BNCT requires boron-containing compounds that exhibit high tumor selectivity...

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Bibliographic Details
Main Authors: Daniela Imperio, Ian Postuma, Salvatore Villani, Erika Del Grosso, Laura Cansolino, Cinzia Ferrari, Silvia Fallarini, Silva Bortolussi, Luigi Panza
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceuticals
Subjects:
autoradiography
saccharides
targeted medicine
boron
glioma cells
click chemistry
Online Access:https://www.mdpi.com/1424-8247/18/7/986
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