Extraction of Polyphenols from Cydonia Oblonga Leaves and Their Effect on Mitochondrial Membrane Stability
Cydonia oblonga Mill. (quince) is a fruit tree native to Azerbaijan, Dagestan, Turkmenistan, and Iran, known by various names including Baher Dana in Urdu and Behi in Hindi. Widely cultivated in Portugal, Turkey, Central Asia, India, and Europe, quince cultivars vary in flowering time and yield. Hig...
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EDP Sciences
2025-01-01
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| Series: | BIO Web of Conferences |
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| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2025/02/bioconf_mblc2024_04033.pdf |
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| author | Matmurotov Bakhtishod Madrakhimova Sakhiba Soliyev Nuriddin Matchanov Alimjan |
| author_facet | Matmurotov Bakhtishod Madrakhimova Sakhiba Soliyev Nuriddin Matchanov Alimjan |
| author_sort | Matmurotov Bakhtishod |
| collection | DOAJ |
| description | Cydonia oblonga Mill. (quince) is a fruit tree native to Azerbaijan, Dagestan, Turkmenistan, and Iran, known by various names including Baher Dana in Urdu and Behi in Hindi. Widely cultivated in Portugal, Turkey, Central Asia, India, and Europe, quince cultivars vary in flowering time and yield. High-yielding cultivars such as Aurora, Zoloto Skif, and Sophia show strong environmental adaptation. New cultivars such as Zolotistaya (28.4 mg/100 g vitamin C) and Padarok (32.3 mg/100 g) are rich in vitamin C and catechins. Phenolic compounds in quince leaves, particularly tannins (11%), have antidiarrheal properties. Extraction methods showed high phenolic content when the leaves were dried at optimal temperatures and extracted using ethanol systems. Quince polyphenols exhibit antioxidant and membrane stabilizing effects, which were observed in mitochondria under Fe2+/ascorbate stress, with inhibition values up to 90.3% at 30 μg/mL PF-4 extract. The study concludes that quince leaf extracts have significant antioxidant potential for pharmaceutical applications. |
| format | Article |
| id | doaj-art-1a71eb0e6d53493e97dbc2b71bc0bbe1 |
| institution | Kabale University |
| issn | 2117-4458 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj-art-1a71eb0e6d53493e97dbc2b71bc0bbe12025-02-05T10:42:42ZengEDP SciencesBIO Web of Conferences2117-44582025-01-011510403310.1051/bioconf/202515104033bioconf_mblc2024_04033Extraction of Polyphenols from Cydonia Oblonga Leaves and Their Effect on Mitochondrial Membrane StabilityMatmurotov Bakhtishod0Madrakhimova Sakhiba1Soliyev Nuriddin2Matchanov Alimjan3Tashkent Medical AcademyAcademy of Sciences of the Republic of UzbekistanNamangan State UniversityAcademy of Sciences of the Republic of UzbekistanCydonia oblonga Mill. (quince) is a fruit tree native to Azerbaijan, Dagestan, Turkmenistan, and Iran, known by various names including Baher Dana in Urdu and Behi in Hindi. Widely cultivated in Portugal, Turkey, Central Asia, India, and Europe, quince cultivars vary in flowering time and yield. High-yielding cultivars such as Aurora, Zoloto Skif, and Sophia show strong environmental adaptation. New cultivars such as Zolotistaya (28.4 mg/100 g vitamin C) and Padarok (32.3 mg/100 g) are rich in vitamin C and catechins. Phenolic compounds in quince leaves, particularly tannins (11%), have antidiarrheal properties. Extraction methods showed high phenolic content when the leaves were dried at optimal temperatures and extracted using ethanol systems. Quince polyphenols exhibit antioxidant and membrane stabilizing effects, which were observed in mitochondria under Fe2+/ascorbate stress, with inhibition values up to 90.3% at 30 μg/mL PF-4 extract. The study concludes that quince leaf extracts have significant antioxidant potential for pharmaceutical applications.https://www.bio-conferences.org/articles/bioconf/pdf/2025/02/bioconf_mblc2024_04033.pdfpolyphenolcydonia oblonga miller (cоm)mitochondriamembraneextractdifferential centrifugationconcentrationextractionsuspensionеthylenediaminetetraoxusnaya acid (еdta) |
| spellingShingle | Matmurotov Bakhtishod Madrakhimova Sakhiba Soliyev Nuriddin Matchanov Alimjan Extraction of Polyphenols from Cydonia Oblonga Leaves and Their Effect on Mitochondrial Membrane Stability BIO Web of Conferences polyphenol cydonia oblonga miller (cоm) mitochondria membrane extract differential centrifugation concentration extraction suspension еthylenediaminetetraoxusnaya acid (еdta) |
| title | Extraction of Polyphenols from Cydonia Oblonga Leaves and Their Effect on Mitochondrial Membrane Stability |
| title_full | Extraction of Polyphenols from Cydonia Oblonga Leaves and Their Effect on Mitochondrial Membrane Stability |
| title_fullStr | Extraction of Polyphenols from Cydonia Oblonga Leaves and Their Effect on Mitochondrial Membrane Stability |
| title_full_unstemmed | Extraction of Polyphenols from Cydonia Oblonga Leaves and Their Effect on Mitochondrial Membrane Stability |
| title_short | Extraction of Polyphenols from Cydonia Oblonga Leaves and Their Effect on Mitochondrial Membrane Stability |
| title_sort | extraction of polyphenols from cydonia oblonga leaves and their effect on mitochondrial membrane stability |
| topic | polyphenol cydonia oblonga miller (cоm) mitochondria membrane extract differential centrifugation concentration extraction suspension еthylenediaminetetraoxusnaya acid (еdta) |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2025/02/bioconf_mblc2024_04033.pdf |
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