Advances in the generation of erythrocytes from stem cells in vitro
Red blood cell transfusion is the main treatment to improve anemia caused by many reasons and has important clinical application value. However, the supply of red blood cells at home and abroad is currently very tight. Therefore, the utilization of stem cells to prepare erythrocytes for clinical use...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Hematology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/16078454.2024.2427932 |
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| author | Yating Ling Hailin Du Yu Zhang Qiang Fu Chengtao He |
| author_facet | Yating Ling Hailin Du Yu Zhang Qiang Fu Chengtao He |
| author_sort | Yating Ling |
| collection | DOAJ |
| description | Red blood cell transfusion is the main treatment to improve anemia caused by many reasons and has important clinical application value. However, the supply of red blood cells at home and abroad is currently very tight. Therefore, the utilization of stem cells to prepare erythrocytes for clinical use is expected to become a new mode of blood supply and security in the future. This review describes the process of erythropoiesis regulation in vivo, summarizes the latest research progress of in vitro erythropoiesis, and points out the current challenges of in vitro erythropoiesis, which is expected to provide a new idea for solving the problem of insufficient clinical erythropoiesis supply. |
| format | Article |
| id | doaj-art-1a6a88852f8b4e2ca35b12d9785b923f |
| institution | DOAJ |
| issn | 1607-8454 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Hematology |
| spelling | doaj-art-1a6a88852f8b4e2ca35b12d9785b923f2025-08-20T02:50:19ZengTaylor & Francis GroupHematology1607-84542024-12-0129110.1080/16078454.2024.2427932Advances in the generation of erythrocytes from stem cells in vitroYating Ling0Hailin Du1Yu Zhang2Qiang Fu3Chengtao He4Department of Laboratory Medicine, Nanjing Red Cross Blood Center, Nanjing, Jiangsu, People’s Republic of ChinaDepartment of Laboratory Medicine, Nanjing Red Cross Blood Center, Nanjing, Jiangsu, People’s Republic of ChinaDepartment of Laboratory Medicine, Nanjing Red Cross Blood Center, Nanjing, Jiangsu, People’s Republic of ChinaDepartment of Laboratory Medicine, Nanjing Red Cross Blood Center, Nanjing, Jiangsu, People’s Republic of ChinaDepartment of Laboratory Medicine, Nanjing Red Cross Blood Center, Nanjing, Jiangsu, People’s Republic of ChinaRed blood cell transfusion is the main treatment to improve anemia caused by many reasons and has important clinical application value. However, the supply of red blood cells at home and abroad is currently very tight. Therefore, the utilization of stem cells to prepare erythrocytes for clinical use is expected to become a new mode of blood supply and security in the future. This review describes the process of erythropoiesis regulation in vivo, summarizes the latest research progress of in vitro erythropoiesis, and points out the current challenges of in vitro erythropoiesis, which is expected to provide a new idea for solving the problem of insufficient clinical erythropoiesis supply.https://www.tandfonline.com/doi/10.1080/16078454.2024.2427932Erythrocytesstem cellsdifferentiationin vitro inductionred bloodcytokine |
| spellingShingle | Yating Ling Hailin Du Yu Zhang Qiang Fu Chengtao He Advances in the generation of erythrocytes from stem cells in vitro Hematology Erythrocytes stem cells differentiation in vitro induction red blood cytokine |
| title | Advances in the generation of erythrocytes from stem cells in vitro |
| title_full | Advances in the generation of erythrocytes from stem cells in vitro |
| title_fullStr | Advances in the generation of erythrocytes from stem cells in vitro |
| title_full_unstemmed | Advances in the generation of erythrocytes from stem cells in vitro |
| title_short | Advances in the generation of erythrocytes from stem cells in vitro |
| title_sort | advances in the generation of erythrocytes from stem cells in vitro |
| topic | Erythrocytes stem cells differentiation in vitro induction red blood cytokine |
| url | https://www.tandfonline.com/doi/10.1080/16078454.2024.2427932 |
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