Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Different Generations of Amplatzer Devices: Multicenter Experience
Objectives. To demonstrate safety and efficacy of using different generations of softer Amplatzer™ devices for ventricular septal defect (VSD) closure to avoid serious complications at follow-up. Background. Transcatheter closure of perimembranous ventricular septal defects (PmVSD) is a well-establi...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Interventional Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2020/8948249 |
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| author | Roberto Mijangos-Vázquez Amal El-Sisi Juan P. Sandoval Jones José A. García-Montes Rogelio Hernández-Reyes Rodina Sobhy Antoine Abdelmassih Mohammed M. Soliman Safaa Ali Tatiana Molina-Sánchez Carlos Zabal |
| author_facet | Roberto Mijangos-Vázquez Amal El-Sisi Juan P. Sandoval Jones José A. García-Montes Rogelio Hernández-Reyes Rodina Sobhy Antoine Abdelmassih Mohammed M. Soliman Safaa Ali Tatiana Molina-Sánchez Carlos Zabal |
| author_sort | Roberto Mijangos-Vázquez |
| collection | DOAJ |
| description | Objectives. To demonstrate safety and efficacy of using different generations of softer Amplatzer™ devices for ventricular septal defect (VSD) closure to avoid serious complications at follow-up. Background. Transcatheter closure of perimembranous ventricular septal defects (PmVSD) is a well-established procedure; however, it is associated with unacceptable incidence of complete heart block. Great advantages have been achieved by using softer devices for VSD transcatheter closure. The first and second generation of Amplatzer™ occluders (AVP II, ADO, and ADO II) seem to offer a safe and attractive alternative for this procedure. These devices can be delivered using either an arterial (retrograde) or venous (prograde) approach. Methods and Results. Patients with congenital PmVSD who underwent transcatheter closure using ADO, ADO II, and AVP II devices were included. Primary end point was to determine efficacy and safety of these generations of devices and to determine the incidence of complications at follow-up (complete AV block and aortic/tricuspid/mitral regurgitation). One hundred and nineteen patients underwent VSD closure at a median age of 5 years (8 months–54 years). During the catheterization, there were only minor complications and at follow-up of 36 ± 25.7 months (up to 99 months), the closure rate was high of 98.3% and freedom from AV block was 100%. Conclusions. The use of softer Amplatzer™ devices is a good alternative to achieve PmVSD closure safely with no risk of AVB during the procedure or at midterm follow-up. |
| format | Article |
| id | doaj-art-1a64c4c8e7334befbeb0d446e0ec40ce |
| institution | Kabale University |
| issn | 0896-4327 1540-8183 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Interventional Cardiology |
| spelling | doaj-art-1a64c4c8e7334befbeb0d446e0ec40ce2025-08-20T03:54:23ZengWileyJournal of Interventional Cardiology0896-43271540-81832020-01-01202010.1155/2020/89482498948249Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Different Generations of Amplatzer Devices: Multicenter ExperienceRoberto Mijangos-Vázquez0Amal El-Sisi1Juan P. Sandoval Jones2José A. García-Montes3Rogelio Hernández-Reyes4Rodina Sobhy5Antoine Abdelmassih6Mohammed M. Soliman7Safaa Ali8Tatiana Molina-Sánchez9Carlos Zabal10Pediatric Interventional Cardiology Department, Pediatric Specialties Hospital, Tuxtla Gutiérrez, Chiapas, MexicoPediatric Department of Faculty of Medicine, Cairo University Children Hospital, Cairo, EgyptPediatric Interventional Cardiology Department, National Institute of Cardiology “Ignacio Chávez”, Mexico City, MexicoPediatric Interventional Cardiology Department, National Institute of Cardiology “Ignacio Chávez”, Mexico City, MexicoPediatric Interventional Cardiology Department, Pediatric Specialties Hospital, Tuxtla Gutiérrez, Chiapas, MexicoPediatric Department of Faculty of Medicine, Cairo University Children Hospital, Cairo, EgyptPediatric Department of Faculty of Medicine, Cairo University Children Hospital, Cairo, EgyptPediatric Department of Faculty of Medicine, Cairo University Children Hospital, Cairo, EgyptPediatric Department of Faculty of Medicine, Sohag University Hospital, Sohag, EgyptPediatric Interventional Cardiology Department, National Institute of Cardiology “Ignacio Chávez”, Mexico City, MexicoPediatric Interventional Cardiology Department, National Institute of Cardiology “Ignacio Chávez”, Mexico City, MexicoObjectives. To demonstrate safety and efficacy of using different generations of softer Amplatzer™ devices for ventricular septal defect (VSD) closure to avoid serious complications at follow-up. Background. Transcatheter closure of perimembranous ventricular septal defects (PmVSD) is a well-established procedure; however, it is associated with unacceptable incidence of complete heart block. Great advantages have been achieved by using softer devices for VSD transcatheter closure. The first and second generation of Amplatzer™ occluders (AVP II, ADO, and ADO II) seem to offer a safe and attractive alternative for this procedure. These devices can be delivered using either an arterial (retrograde) or venous (prograde) approach. Methods and Results. Patients with congenital PmVSD who underwent transcatheter closure using ADO, ADO II, and AVP II devices were included. Primary end point was to determine efficacy and safety of these generations of devices and to determine the incidence of complications at follow-up (complete AV block and aortic/tricuspid/mitral regurgitation). One hundred and nineteen patients underwent VSD closure at a median age of 5 years (8 months–54 years). During the catheterization, there were only minor complications and at follow-up of 36 ± 25.7 months (up to 99 months), the closure rate was high of 98.3% and freedom from AV block was 100%. Conclusions. The use of softer Amplatzer™ devices is a good alternative to achieve PmVSD closure safely with no risk of AVB during the procedure or at midterm follow-up.http://dx.doi.org/10.1155/2020/8948249 |
| spellingShingle | Roberto Mijangos-Vázquez Amal El-Sisi Juan P. Sandoval Jones José A. García-Montes Rogelio Hernández-Reyes Rodina Sobhy Antoine Abdelmassih Mohammed M. Soliman Safaa Ali Tatiana Molina-Sánchez Carlos Zabal Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Different Generations of Amplatzer Devices: Multicenter Experience Journal of Interventional Cardiology |
| title | Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Different Generations of Amplatzer Devices: Multicenter Experience |
| title_full | Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Different Generations of Amplatzer Devices: Multicenter Experience |
| title_fullStr | Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Different Generations of Amplatzer Devices: Multicenter Experience |
| title_full_unstemmed | Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Different Generations of Amplatzer Devices: Multicenter Experience |
| title_short | Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Different Generations of Amplatzer Devices: Multicenter Experience |
| title_sort | transcatheter closure of perimembranous ventricular septal defects using different generations of amplatzer devices multicenter experience |
| url | http://dx.doi.org/10.1155/2020/8948249 |
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