Sex and age differences in glia and myelin in nonhuman primate and human spinal cords: implications for pathology

Abstract In a healthy central nervous system, glial cells are influenced by genetic, epigenetic, age, and sex factors. Aging typically causes astrocytes and microglia to undergo changes that reduce their neuroprotective functions and increase harmful activities. Additionally, sex-related differences...

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Main Authors: Gaëtan Poulen, Nacéra Douich, Chloé M. Gazard, Nadine Mestre-Francés, Maïda Cardoso, Luc Bauchet, Florence Vachiery-Lahaye, Nicolas Lonjon, Yannick N. Gerber, Florence E. Perrin
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02425-9
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