Genomic prediction of bone strength in laying hens using different sources of information

Bone damage in laying hens remains a significant welfare concern in the egg industry. Breeding companies rely on selective cross-breeding of purebred birds to produce commercial hybrids, which farmers raise for table-egg production. Genomic prediction is a potential tool to improve bone quality in l...

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Main Authors: M. Sallam, H. Wall, P.W. Wilson, B. Andersson, M. Schmutz, C. Benavides, M. Checa, E. Sanchez‑Rodriguez, A.B. Rodriguez‑Navarro, A. Kindmark, I.C. Dunn, D‑J. de Koning, M. Johnsson
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Animal
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Online Access:http://www.sciencedirect.com/science/article/pii/S1751731125000357
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author M. Sallam
H. Wall
P.W. Wilson
B. Andersson
M. Schmutz
C. Benavides
M. Checa
E. Sanchez‑Rodriguez
A.B. Rodriguez‑Navarro
A. Kindmark
I.C. Dunn
D‑J. de Koning
M. Johnsson
author_facet M. Sallam
H. Wall
P.W. Wilson
B. Andersson
M. Schmutz
C. Benavides
M. Checa
E. Sanchez‑Rodriguez
A.B. Rodriguez‑Navarro
A. Kindmark
I.C. Dunn
D‑J. de Koning
M. Johnsson
author_sort M. Sallam
collection DOAJ
description Bone damage in laying hens remains a significant welfare concern in the egg industry. Breeding companies rely on selective cross-breeding of purebred birds to produce commercial hybrids, which farmers raise for table-egg production. Genomic prediction is a potential tool to improve bone quality in laying hens. Because commercial layers are crossbred and kept in different environments than pure lines, the question arises whether to use within-line purebred selection or whether to use crossbred data. While selection based on pure line data is common, achieving optimal bone strength in hybrids may require incorporating hybrid data to account for heterosis and housing-specific effects. This study aims to evaluate how combining pure line and hybrid data could affect the accuracy of breeding values for bone strength. Genotypes and phenotypes were available from two types of white hybrids (Bovans White and Lohmann Selected Leghorn Classic) housed in two housing systems (furnished cages and floor housing). This resulted in four hybrid-housing combinations (n ∼ 220 for each). Tibia strength and genotypes for pure breeding lines of White Leghorn (WL, n = 947) and Rhode Island Red (RIR, n = 924) were also included. Each of the hybrid-housing combinations and pure lines was fitted separately into (1) single-trait Genomic Best Linear Unbiased Prediction (GBLUP), then simultaneously via multitrait GBLUP, (2) within hybrids across housing, (3) across hybrids within housing, (4) across hybrids and housing, (5) the latter in combination with WL and/or RIR data. Including hybrid data slightly increased the accuracy of the genomic estimated breeding value (GEBV) of other hybrids, but not that of pure lines. Pure line data increased the GEBV accuracy of hybrids over and above that of combining hybrid information. Combining data from two pure lines improved the GEBV accuracy of both. In comparison to the combination of data across lines and/or houses, combining tibia strength and BW within-lines increased tibia strength GEBV accuracy. The maximum GEBV accuracy obtained for tibia strength ranged from 0.42 to 0.65 for hybrids and from 0.63 to 0.78 for pure lines. Further study is required to test whether modelling the interactions of genotype by environment could help to breed hybrids for specific housing systems.
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spelling doaj-art-1a5e7e584e4f4bc6b4cd2d7fe83228662025-08-20T02:02:05ZengElsevierAnimal1751-73112025-03-0119310145210.1016/j.animal.2025.101452Genomic prediction of bone strength in laying hens using different sources of informationM. Sallam0H. Wall1P.W. Wilson2B. Andersson3M. Schmutz4C. Benavides5M. Checa6E. Sanchez‑Rodriguez7A.B. Rodriguez‑Navarro8A. Kindmark9I.C. Dunn10D‑J. de Koning11M. Johnsson12Department of Animal Biosciences, Swedish University of Agricultural Sciences, 75651 Uppsala, SwedenDepartment of Animal Biosciences, Swedish University of Agricultural Sciences, 75651 Uppsala, SwedenRoslin Institute, University of Edinburgh, Edinburgh EH25 9RG Scotland, UKLohmann Breeders, 27472 Cuxhaven, GermanyLohmann Breeders, 27472 Cuxhaven, GermanyDepartamento de Mineralogia y Petrologia, Universidad de Granada,18002 Granada, SpainDepartamento de Mineralogia y Petrologia, Universidad de Granada,18002 Granada, SpainDepartamento de Mineralogia y Petrologia, Universidad de Granada,18002 Granada, SpainDepartamento de Mineralogia y Petrologia, Universidad de Granada,18002 Granada, SpainDepartment of Medical Sciences, Uppsala University, Akademiska sjukhuset, 751 85 Uppsala, SwedenRoslin Institute, University of Edinburgh, Edinburgh EH25 9RG Scotland, UKDepartment of Animal Biosciences, Swedish University of Agricultural Sciences, 75651 Uppsala, SwedenDepartment of Animal Biosciences, Swedish University of Agricultural Sciences, 75651 Uppsala, Sweden; Corresponding author.Bone damage in laying hens remains a significant welfare concern in the egg industry. Breeding companies rely on selective cross-breeding of purebred birds to produce commercial hybrids, which farmers raise for table-egg production. Genomic prediction is a potential tool to improve bone quality in laying hens. Because commercial layers are crossbred and kept in different environments than pure lines, the question arises whether to use within-line purebred selection or whether to use crossbred data. While selection based on pure line data is common, achieving optimal bone strength in hybrids may require incorporating hybrid data to account for heterosis and housing-specific effects. This study aims to evaluate how combining pure line and hybrid data could affect the accuracy of breeding values for bone strength. Genotypes and phenotypes were available from two types of white hybrids (Bovans White and Lohmann Selected Leghorn Classic) housed in two housing systems (furnished cages and floor housing). This resulted in four hybrid-housing combinations (n ∼ 220 for each). Tibia strength and genotypes for pure breeding lines of White Leghorn (WL, n = 947) and Rhode Island Red (RIR, n = 924) were also included. Each of the hybrid-housing combinations and pure lines was fitted separately into (1) single-trait Genomic Best Linear Unbiased Prediction (GBLUP), then simultaneously via multitrait GBLUP, (2) within hybrids across housing, (3) across hybrids within housing, (4) across hybrids and housing, (5) the latter in combination with WL and/or RIR data. Including hybrid data slightly increased the accuracy of the genomic estimated breeding value (GEBV) of other hybrids, but not that of pure lines. Pure line data increased the GEBV accuracy of hybrids over and above that of combining hybrid information. Combining data from two pure lines improved the GEBV accuracy of both. In comparison to the combination of data across lines and/or houses, combining tibia strength and BW within-lines increased tibia strength GEBV accuracy. The maximum GEBV accuracy obtained for tibia strength ranged from 0.42 to 0.65 for hybrids and from 0.63 to 0.78 for pure lines. Further study is required to test whether modelling the interactions of genotype by environment could help to breed hybrids for specific housing systems.http://www.sciencedirect.com/science/article/pii/S1751731125000357Cage-freeCrossbredFurnished cagesMultitraitPurebred
spellingShingle M. Sallam
H. Wall
P.W. Wilson
B. Andersson
M. Schmutz
C. Benavides
M. Checa
E. Sanchez‑Rodriguez
A.B. Rodriguez‑Navarro
A. Kindmark
I.C. Dunn
D‑J. de Koning
M. Johnsson
Genomic prediction of bone strength in laying hens using different sources of information
Animal
Cage-free
Crossbred
Furnished cages
Multitrait
Purebred
title Genomic prediction of bone strength in laying hens using different sources of information
title_full Genomic prediction of bone strength in laying hens using different sources of information
title_fullStr Genomic prediction of bone strength in laying hens using different sources of information
title_full_unstemmed Genomic prediction of bone strength in laying hens using different sources of information
title_short Genomic prediction of bone strength in laying hens using different sources of information
title_sort genomic prediction of bone strength in laying hens using different sources of information
topic Cage-free
Crossbred
Furnished cages
Multitrait
Purebred
url http://www.sciencedirect.com/science/article/pii/S1751731125000357
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