Investigating the activity of Bacillus subtilis and Trichoderma harzianum to mitigate Fusarium wilt disease of diverse cultivars of Vicia faba

Abstract Fusarium wilt causes destructive effects on Vicia faba (VF). This study is innovative because it evaluates the comparative effects of various biological treatments on different VF cultivars to determine the therapeutic potential of each treatment against Fusarium wilt. In this study, the su...

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Main Authors: Mohamed S. Attia, Deiaa A. El-Wakil, Amr H. Hashem, Abdulaziz A. Al-Askar, Hamada AbdElgawad, Rawan Saif Alotaibi, Saad. A. Abdel-Kader, Amer M. Abdelaziz
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Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-99381-2
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author Mohamed S. Attia
Deiaa A. El-Wakil
Amr H. Hashem
Abdulaziz A. Al-Askar
Hamada AbdElgawad
Rawan Saif Alotaibi
Saad. A. Abdel-Kader
Amer M. Abdelaziz
author_facet Mohamed S. Attia
Deiaa A. El-Wakil
Amr H. Hashem
Abdulaziz A. Al-Askar
Hamada AbdElgawad
Rawan Saif Alotaibi
Saad. A. Abdel-Kader
Amer M. Abdelaziz
author_sort Mohamed S. Attia
collection DOAJ
description Abstract Fusarium wilt causes destructive effects on Vicia faba (VF). This study is innovative because it evaluates the comparative effects of various biological treatments on different VF cultivars to determine the therapeutic potential of each treatment against Fusarium wilt. In this study, the suppression of F. verticillioides (FV) by Bacillus subtilis and Trichoderma harzianum was compared at both the pot level and in vitro. The findings indicated that both B. subtilis and T. harzianum have antifungal effects on F. verticillioides in vitro, exhibiting mycelium inhibition percentages of 45.88% and 68.20%. Our results showed that treatments with T. harzianum significantly reduced the disease incidence (DI) in both the V. faba ‘Giza-716’ (G) and ‘Sakha-101’ (S) cultivars, providing comparable protection at 70.58% and 72.22%, respectively. After the afflicted plant received biological therapies, a notable increase in all yield components was observed. The G and S cultivars treated with T. harzianum exhibited the highest PPO activity, measuring 116.70% and 227.70%. The S cultivar treated with T. harzianum showed the highest POD activity at 289.60%. In conclusion, T. harzianum and B. subtilis as potential bio pesticides exhibited high efficacy against F. verticillioides, which causes wilt in several Vicia faba cultivars, due to their effectiveness and environmental friendliness.
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spelling doaj-art-1a579a2f660d49ca83dc96574a7e16c22025-08-20T03:53:12ZengNature PortfolioScientific Reports2045-23222025-05-0115111410.1038/s41598-025-99381-2Investigating the activity of Bacillus subtilis and Trichoderma harzianum to mitigate Fusarium wilt disease of diverse cultivars of Vicia fabaMohamed S. Attia0Deiaa A. El-Wakil1Amr H. Hashem2Abdulaziz A. Al-Askar3Hamada AbdElgawad4Rawan Saif Alotaibi5Saad. A. Abdel-Kader6Amer M. Abdelaziz7Department of Botany and Microbiology, Faculty of Science, Al-Azhar UniversitySeed Pathology Research Department, Plant Pathology Research Institute, Agricultural Research CenterDepartment of Botany and Microbiology, Faculty of Science, Al-Azhar UniversityDepartment of Botany and Microbiology, Faculty of Science, King Saud UniversityIntegrated Molecular Plant Physiology Research, Department of Biology, University of AntwerpDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman UniversityPlant Protection Department, Faculty of Agriculture, Al-Azhar UniversityDepartment of Botany and Microbiology, Faculty of Science, Al-Azhar UniversityAbstract Fusarium wilt causes destructive effects on Vicia faba (VF). This study is innovative because it evaluates the comparative effects of various biological treatments on different VF cultivars to determine the therapeutic potential of each treatment against Fusarium wilt. In this study, the suppression of F. verticillioides (FV) by Bacillus subtilis and Trichoderma harzianum was compared at both the pot level and in vitro. The findings indicated that both B. subtilis and T. harzianum have antifungal effects on F. verticillioides in vitro, exhibiting mycelium inhibition percentages of 45.88% and 68.20%. Our results showed that treatments with T. harzianum significantly reduced the disease incidence (DI) in both the V. faba ‘Giza-716’ (G) and ‘Sakha-101’ (S) cultivars, providing comparable protection at 70.58% and 72.22%, respectively. After the afflicted plant received biological therapies, a notable increase in all yield components was observed. The G and S cultivars treated with T. harzianum exhibited the highest PPO activity, measuring 116.70% and 227.70%. The S cultivar treated with T. harzianum showed the highest POD activity at 289.60%. In conclusion, T. harzianum and B. subtilis as potential bio pesticides exhibited high efficacy against F. verticillioides, which causes wilt in several Vicia faba cultivars, due to their effectiveness and environmental friendliness.https://doi.org/10.1038/s41598-025-99381-2FusariumVicia fabaTrichodermaBiocontrolFungicidal
spellingShingle Mohamed S. Attia
Deiaa A. El-Wakil
Amr H. Hashem
Abdulaziz A. Al-Askar
Hamada AbdElgawad
Rawan Saif Alotaibi
Saad. A. Abdel-Kader
Amer M. Abdelaziz
Investigating the activity of Bacillus subtilis and Trichoderma harzianum to mitigate Fusarium wilt disease of diverse cultivars of Vicia faba
Scientific Reports
Fusarium
Vicia faba
Trichoderma
Biocontrol
Fungicidal
title Investigating the activity of Bacillus subtilis and Trichoderma harzianum to mitigate Fusarium wilt disease of diverse cultivars of Vicia faba
title_full Investigating the activity of Bacillus subtilis and Trichoderma harzianum to mitigate Fusarium wilt disease of diverse cultivars of Vicia faba
title_fullStr Investigating the activity of Bacillus subtilis and Trichoderma harzianum to mitigate Fusarium wilt disease of diverse cultivars of Vicia faba
title_full_unstemmed Investigating the activity of Bacillus subtilis and Trichoderma harzianum to mitigate Fusarium wilt disease of diverse cultivars of Vicia faba
title_short Investigating the activity of Bacillus subtilis and Trichoderma harzianum to mitigate Fusarium wilt disease of diverse cultivars of Vicia faba
title_sort investigating the activity of bacillus subtilis and trichoderma harzianum to mitigate fusarium wilt disease of diverse cultivars of vicia faba
topic Fusarium
Vicia faba
Trichoderma
Biocontrol
Fungicidal
url https://doi.org/10.1038/s41598-025-99381-2
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