Physical activity during pregnancy and offspring neurodevelopment and IQ in the first 4 years of life.

<h4>Background</h4>Maternal physical activity during pregnancy could alter offspring's IQ and neurodevelopment in childhood.<h4>Methods</h4>Children belonging to a birth cohort were followed at 3, 12, 24 and 48 months of age. Physical activity during pregnancy was assess...

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Main Authors: Marlos R Domingues, Alicia Matijasevich, Aluísio J D Barros, Iná S Santos, Bernardo L Horta, Pedro C Hallal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0110050
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author Marlos R Domingues
Alicia Matijasevich
Aluísio J D Barros
Iná S Santos
Bernardo L Horta
Pedro C Hallal
author_facet Marlos R Domingues
Alicia Matijasevich
Aluísio J D Barros
Iná S Santos
Bernardo L Horta
Pedro C Hallal
author_sort Marlos R Domingues
collection DOAJ
description <h4>Background</h4>Maternal physical activity during pregnancy could alter offspring's IQ and neurodevelopment in childhood.<h4>Methods</h4>Children belonging to a birth cohort were followed at 3, 12, 24 and 48 months of age. Physical activity during pregnancy was assessed retrospectively at birth. Neurodevelopment was evaluated by Battelle's Development Inventory (12, 24 and 48 months) and IQ by the Weschler's Intelligence Scale (48 months). Neurodevelopment was based on Battelles' (90th percentile) and also analyzed as a continuous outcome. IQ was analyzed as a continuous outcome. Potential confounders were: family income, mother's age, schooling, skin color, number of previous births and smoking; and newborns': preterm birth, sex and low birth weight.<h4>Results</h4>From birth to 48 months, sample size decreased from 4231 to 3792. Crude analysis showed that IQ at 48 months was slightly higher (5 points) among children from active women. The Battelle's score at 12 and 24 months was higher among offspring from active mothers. After controlling for confounders, physical activity during pregnancy was positively associated to the Battelle's Inventory at 12 months IQ, however, at 48 months no association was observed.<h4>Conclusion</h4>Physical activity during pregnancy does not seem to impair children's neurodevelopment and children from active mothers presented better performance at 12 months.
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spelling doaj-art-1a46eb153cda494a8d2cd0f8024a882a2025-08-20T03:10:06ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-01910e11005010.1371/journal.pone.0110050Physical activity during pregnancy and offspring neurodevelopment and IQ in the first 4 years of life.Marlos R DominguesAlicia MatijasevichAluísio J D BarrosIná S SantosBernardo L HortaPedro C Hallal<h4>Background</h4>Maternal physical activity during pregnancy could alter offspring's IQ and neurodevelopment in childhood.<h4>Methods</h4>Children belonging to a birth cohort were followed at 3, 12, 24 and 48 months of age. Physical activity during pregnancy was assessed retrospectively at birth. Neurodevelopment was evaluated by Battelle's Development Inventory (12, 24 and 48 months) and IQ by the Weschler's Intelligence Scale (48 months). Neurodevelopment was based on Battelles' (90th percentile) and also analyzed as a continuous outcome. IQ was analyzed as a continuous outcome. Potential confounders were: family income, mother's age, schooling, skin color, number of previous births and smoking; and newborns': preterm birth, sex and low birth weight.<h4>Results</h4>From birth to 48 months, sample size decreased from 4231 to 3792. Crude analysis showed that IQ at 48 months was slightly higher (5 points) among children from active women. The Battelle's score at 12 and 24 months was higher among offspring from active mothers. After controlling for confounders, physical activity during pregnancy was positively associated to the Battelle's Inventory at 12 months IQ, however, at 48 months no association was observed.<h4>Conclusion</h4>Physical activity during pregnancy does not seem to impair children's neurodevelopment and children from active mothers presented better performance at 12 months.https://doi.org/10.1371/journal.pone.0110050
spellingShingle Marlos R Domingues
Alicia Matijasevich
Aluísio J D Barros
Iná S Santos
Bernardo L Horta
Pedro C Hallal
Physical activity during pregnancy and offspring neurodevelopment and IQ in the first 4 years of life.
PLoS ONE
title Physical activity during pregnancy and offspring neurodevelopment and IQ in the first 4 years of life.
title_full Physical activity during pregnancy and offspring neurodevelopment and IQ in the first 4 years of life.
title_fullStr Physical activity during pregnancy and offspring neurodevelopment and IQ in the first 4 years of life.
title_full_unstemmed Physical activity during pregnancy and offspring neurodevelopment and IQ in the first 4 years of life.
title_short Physical activity during pregnancy and offspring neurodevelopment and IQ in the first 4 years of life.
title_sort physical activity during pregnancy and offspring neurodevelopment and iq in the first 4 years of life
url https://doi.org/10.1371/journal.pone.0110050
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