HIV infection and cardiovascular pathology
According to modern literature data, the role of human immunodeficiency virus (HIV) infection has been proven as an independent risk factor (RF) for atherosclerosis and cardiovascular diseases (CVDs), including coronary artery disease, heart failure, and sudden cardiac death. The role of antiretrovi...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2023-04-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/3370 |
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| author | T. A. Shekhovtsova D. V. Duplyakov |
| author_facet | T. A. Shekhovtsova D. V. Duplyakov |
| author_sort | T. A. Shekhovtsova |
| collection | DOAJ |
| description | According to modern literature data, the role of human immunodeficiency virus (HIV) infection has been proven as an independent risk factor (RF) for atherosclerosis and cardiovascular diseases (CVDs), including coronary artery disease, heart failure, and sudden cardiac death. The role of antiretroviral therapy (ART) in the occurrence of CVD remains debatable. On the one hand, ART is a mandatory component in CVD prevention, since there are numerous confirmations of the association of high viral load and noncompensated immune status with an increased risk of CVD. On the other hand, the use of certain classes of ART agents is associated with the development of dyslipidemia, insulin resistance, and type 2 diabetes, which are risk factors for CVD. In this regard, the current HIV treatment protocols require an assessment of CVD risk factors to select the optimal ART regimen. It must be remembered that when using generally accepted algorithms and scales for assessing the risk of CVD, the real risk may remain underestimated in HIV-infected patients. This literature review presents a patient data management algorithm developed by the American Heart Association and describes statin therapy in patients with HIV infection. |
| format | Article |
| id | doaj-art-1a460929dfdd4a43b08437578f57d72a |
| institution | DOAJ |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2023-04-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-1a460929dfdd4a43b08437578f57d72a2025-08-20T03:18:48Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252023-04-0122310.15829/1728-8800-2023-33702671HIV infection and cardiovascular pathologyT. A. Shekhovtsova0D. V. Duplyakov1Polyakov Samara Regional Clinical Cardiology DispensaryPolyakov Samara Regional Clinical Cardiology Dispensary; Samara State Medical UniversityAccording to modern literature data, the role of human immunodeficiency virus (HIV) infection has been proven as an independent risk factor (RF) for atherosclerosis and cardiovascular diseases (CVDs), including coronary artery disease, heart failure, and sudden cardiac death. The role of antiretroviral therapy (ART) in the occurrence of CVD remains debatable. On the one hand, ART is a mandatory component in CVD prevention, since there are numerous confirmations of the association of high viral load and noncompensated immune status with an increased risk of CVD. On the other hand, the use of certain classes of ART agents is associated with the development of dyslipidemia, insulin resistance, and type 2 diabetes, which are risk factors for CVD. In this regard, the current HIV treatment protocols require an assessment of CVD risk factors to select the optimal ART regimen. It must be remembered that when using generally accepted algorithms and scales for assessing the risk of CVD, the real risk may remain underestimated in HIV-infected patients. This literature review presents a patient data management algorithm developed by the American Heart Association and describes statin therapy in patients with HIV infection.https://cardiovascular.elpub.ru/jour/article/view/3370human immunodeficiency virusantiretroviral therapycardiovascular diseasesudden cardiac deathheart failureatherosclerosis |
| spellingShingle | T. A. Shekhovtsova D. V. Duplyakov HIV infection and cardiovascular pathology Кардиоваскулярная терапия и профилактика human immunodeficiency virus antiretroviral therapy cardiovascular disease sudden cardiac death heart failure atherosclerosis |
| title | HIV infection and cardiovascular pathology |
| title_full | HIV infection and cardiovascular pathology |
| title_fullStr | HIV infection and cardiovascular pathology |
| title_full_unstemmed | HIV infection and cardiovascular pathology |
| title_short | HIV infection and cardiovascular pathology |
| title_sort | hiv infection and cardiovascular pathology |
| topic | human immunodeficiency virus antiretroviral therapy cardiovascular disease sudden cardiac death heart failure atherosclerosis |
| url | https://cardiovascular.elpub.ru/jour/article/view/3370 |
| work_keys_str_mv | AT tashekhovtsova hivinfectionandcardiovascularpathology AT dvduplyakov hivinfectionandcardiovascularpathology |