Foxo3-mediated physiological cell competition ensures robust tissue patterning throughout vertebrate development
Abstract Unfit cells with defective signalling or gene expression are eliminated through competition with neighbouring cells. However, physiological roles and mechanisms of cell competition in vertebrates remain unclear. In addition, universal mechanisms regulating diverse cell competition are unkno...
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| Main Authors: | Kanako Matsumoto, Yuki Akieda, Yukinari Haraoka, Naoki Hirono, Hiroshi Sasaki, Tohru Ishitani |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-12-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-55108-x |
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