Polymorphism of the Fractalkine Receptor CX3CR1 and Systemic Sclerosis-associated Pulmonary Arterial Hypertension

Polymorphism of the Fractalkine Receptor CX3CR1 and Systemic Sclerosis-associated Pulmonary Arterial Hypertension

Fractalkine (FKN) and its receptor CX3CR1 are critical mediators in the vascular and tissue damage of several chronic diseases, including systemic sclerosis (SSc) and pulmonary arterial hypertension (PAH). Interestingly, the V249I and T280M genetic polymorphism...

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Bibliographic Details
Main Authors: Bianca Marasini, Roberta Cossutta, Carlo Selmi, Maria Rosa Pozzi, Marco Gardinali, Marco Massarotti, Maddalena Erario, Lodovica Battaglioli, Maria Luisa Biondi
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1080/17402520500303297
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