Blockade of Src signaling prevented stemness gene expression and proliferation of patient-derived gastric cancer stem cells

Blockade of Src signaling prevented stemness gene expression and proliferation of patient-derived gastric cancer stem cells

Objectives: Gastric cancer (GC) is one of the most malignant tumors. Mounting studies highlighted gastric cancer stem cells (GCSCs) were responsible for the failure of treatment due to recurrence and drug resistance of advanced GC. However, targeted therapy against GCSC for improving GC prognosis su...

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Bibliographic Details
Main Authors: Chi-Tan Hu, Chen-Fang Lin, Hsiu-Ming Shih, Ren-In You, Wen-Sheng Wu, Yen-Cheng Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Tzu Chi Medical Journal
Subjects:
cancer stem cells
gastric cancer
src
targeted therapy
Online Access:https://journals.lww.com/10.4103/tcmj.tcmj_133_24
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