A short neuropsychological evaluation of patients with primary Sjögren's syndrome

Objective: To investigate cognitive deficits in patients with primary Sjögren’s syndrome (PSS). Method: Eighteen patients with PSS, aged between 25 and 61 years, were subjected to a short neuropsychological battery and compared with 18 patients with multiple sclerosis and 18 healthy controls. Re...

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Main Authors: Dóra-Neide Rodrigues, João Sergio Ignácio Hora, Maria Cecília Fonseca Salgado, Renata Alves Paes, Claudia Cristina Ferreira Vasconcelos, J. Landeira-Fernandez, Regina Maria Papais Alvarenga
Format: Article
Language:English
Published: Thieme Revinter Publicações 2014-01-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000100038&lng=en&tlng=en
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author Dóra-Neide Rodrigues
João Sergio Ignácio Hora
Maria Cecília Fonseca Salgado
Renata Alves Paes
Claudia Cristina Ferreira Vasconcelos
J. Landeira-Fernandez
Regina Maria Papais Alvarenga
author_facet Dóra-Neide Rodrigues
João Sergio Ignácio Hora
Maria Cecília Fonseca Salgado
Renata Alves Paes
Claudia Cristina Ferreira Vasconcelos
J. Landeira-Fernandez
Regina Maria Papais Alvarenga
author_sort Dóra-Neide Rodrigues
collection DOAJ
description Objective: To investigate cognitive deficits in patients with primary Sjögren’s syndrome (PSS). Method: Eighteen patients with PSS, aged between 25 and 61 years, were subjected to a short neuropsychological battery and compared with 18 patients with multiple sclerosis and 18 healthy controls. Results: The analysis of variance (ANOVA) revealed that the clinical groups had significantly worse performance than the control group on the Rey Auditory Verbal Learning Test 3; (F 2,53 =3.500, p=0.038) and 7 (F 2,53 =5.068, p=0.010). The clinical groups had elevated levels of depression on the Beck Depression Inventory (BDI); (p=0.003). The analysis of the data from the Trail Making Test B-A revealed a significant difference between the clinical and control groups (p=0.023). The analysis of covariance with BDI score as a covariate, did not change the outcome. Conclusion: Our study revealed cognitive deficits in patients with PSS detectable by a short neuropsychological battery.
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series Arquivos de Neuro-Psiquiatria
spelling doaj-art-1a259ab6d0e84feeb22e1debf5c209522025-08-20T03:17:52ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272014-01-01721384310.1590/0004-282X20130195S0004-282X2014000100038A short neuropsychological evaluation of patients with primary Sjögren's syndromeDóra-Neide RodriguesJoão Sergio Ignácio HoraMaria Cecília Fonseca SalgadoRenata Alves PaesClaudia Cristina Ferreira VasconcelosJ. Landeira-FernandezRegina Maria Papais AlvarengaObjective: To investigate cognitive deficits in patients with primary Sjögren’s syndrome (PSS). Method: Eighteen patients with PSS, aged between 25 and 61 years, were subjected to a short neuropsychological battery and compared with 18 patients with multiple sclerosis and 18 healthy controls. Results: The analysis of variance (ANOVA) revealed that the clinical groups had significantly worse performance than the control group on the Rey Auditory Verbal Learning Test 3; (F 2,53 =3.500, p=0.038) and 7 (F 2,53 =5.068, p=0.010). The clinical groups had elevated levels of depression on the Beck Depression Inventory (BDI); (p=0.003). The analysis of the data from the Trail Making Test B-A revealed a significant difference between the clinical and control groups (p=0.023). The analysis of covariance with BDI score as a covariate, did not change the outcome. Conclusion: Our study revealed cognitive deficits in patients with PSS detectable by a short neuropsychological battery.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000100038&lng=en&tlng=enavaliação neuropsicológicasíndrome de Sjögrencomprometimento cognitivoneuropsicologia
spellingShingle Dóra-Neide Rodrigues
João Sergio Ignácio Hora
Maria Cecília Fonseca Salgado
Renata Alves Paes
Claudia Cristina Ferreira Vasconcelos
J. Landeira-Fernandez
Regina Maria Papais Alvarenga
A short neuropsychological evaluation of patients with primary Sjögren's syndrome
Arquivos de Neuro-Psiquiatria
avaliação neuropsicológica
síndrome de Sjögren
comprometimento cognitivo
neuropsicologia
title A short neuropsychological evaluation of patients with primary Sjögren's syndrome
title_full A short neuropsychological evaluation of patients with primary Sjögren's syndrome
title_fullStr A short neuropsychological evaluation of patients with primary Sjögren's syndrome
title_full_unstemmed A short neuropsychological evaluation of patients with primary Sjögren's syndrome
title_short A short neuropsychological evaluation of patients with primary Sjögren's syndrome
title_sort short neuropsychological evaluation of patients with primary sjogren s syndrome
topic avaliação neuropsicológica
síndrome de Sjögren
comprometimento cognitivo
neuropsicologia
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000100038&lng=en&tlng=en
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