Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity
Longevity medicine is an emerging and iterative healthcare discipline focusing on early detection, preventive measures, and personalized approaches that aim to extend healthy lifespan and promote healthy aging. This comprehensive review introduces the innovative concept of the “Longevity Pyramid.” T...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-11-01
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| Series: | Frontiers in Aging |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fragi.2024.1495029/full |
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| author | Anđela Martinović Anđela Martinović Matilde Mantovani Matilde Mantovani Natalia Trpchevska Eva Novak Nikolay B. Milev Leonie Bode Collin Y. Ewald Evelyne Bischof Evelyne Bischof Tobias Reichmuth Rebecca Lapides Alexander Navarini Babak Saravi Elisabeth Roider Elisabeth Roider Elisabeth Roider |
| author_facet | Anđela Martinović Anđela Martinović Matilde Mantovani Matilde Mantovani Natalia Trpchevska Eva Novak Nikolay B. Milev Leonie Bode Collin Y. Ewald Evelyne Bischof Evelyne Bischof Tobias Reichmuth Rebecca Lapides Alexander Navarini Babak Saravi Elisabeth Roider Elisabeth Roider Elisabeth Roider |
| author_sort | Anđela Martinović |
| collection | DOAJ |
| description | Longevity medicine is an emerging and iterative healthcare discipline focusing on early detection, preventive measures, and personalized approaches that aim to extend healthy lifespan and promote healthy aging. This comprehensive review introduces the innovative concept of the “Longevity Pyramid.” This conceptual framework delineates progressive intervention levels, providing a structured approach to understanding the diverse strategies available in longevity medicine. At the base of the Longevity Pyramid lies the level of prevention, emphasizing early detection strategies and advanced diagnostics or timely identification of potential health issues. Moving upwards, the next step involves lifestyle modifications, health-promoting behaviors, and proactive measures to delay the onset of age-related conditions. The Longevity Pyramid further explores the vast range of personalized interventions, highlighting the importance of tailoring medical approaches based on genetic predispositions, lifestyle factors, and unique health profiles, thereby optimizing interventions for maximal efficacy. These interventions aim to extend lifespan and reduce the impact and severity of age-related conditions, ensuring that additional years are characterized by vitality and wellbeing. By outlining these progressive levels of intervention, this review offers valuable insights into the evolving field of longevity medicine. This structured framework guides researchers and practitioners toward a nuanced strategic approach to advancing the science and practice of healthy aging. |
| format | Article |
| id | doaj-art-1a2058cf581b49008e6f3ccbcbe9aeb9 |
| institution | OA Journals |
| issn | 2673-6217 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging |
| spelling | doaj-art-1a2058cf581b49008e6f3ccbcbe9aeb92025-08-20T02:23:09ZengFrontiers Media S.A.Frontiers in Aging2673-62172024-11-01510.3389/fragi.2024.14950291495029Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevityAnđela Martinović0Anđela Martinović1Matilde Mantovani2Matilde Mantovani3Natalia Trpchevska4Eva Novak5Nikolay B. Milev6Leonie Bode7Collin Y. Ewald8Evelyne Bischof9Evelyne Bischof10Tobias Reichmuth11Rebecca Lapides12Alexander Navarini13Babak Saravi14Elisabeth Roider15Elisabeth Roider16Elisabeth Roider17Maximon AG, Zug, SwitzerlandDepartment of Food Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, ItalyMaximon AG, Zug, SwitzerlandAvea Life, Zug, SwitzerlandAYUN, Zug, SwitzerlandMaximon AG, Zug, SwitzerlandMaximon AG, Zug, SwitzerlandAYUN, Zug, SwitzerlandLaboratory of Extracellular Matrix Regeneration, Institute of Translational Medicine, Department of Health Sciences and Technology, ETH Zürich, Zürich, SwitzerlandShanghai University of Medicine and Health Sciences, Shanghai, ChinaSheba Longevity Center, Sheba Medical Center Tel Aviv, Ramat Gan, IsraelMaximon AG, Zug, SwitzerlandThe Robert Larner, M.D., College of Medicine at the University of Vermont, Burlington, VT, United StatesDepartment of Dermatology, University Hospital Basel, Basel, Switzerland0Department of Orthopedics and Trauma Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, GermanyMaximon AG, Zug, Switzerland1Department of Dermatology, University Hospital of Basel, Basel, Switzerland2Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United StatesLongevity medicine is an emerging and iterative healthcare discipline focusing on early detection, preventive measures, and personalized approaches that aim to extend healthy lifespan and promote healthy aging. This comprehensive review introduces the innovative concept of the “Longevity Pyramid.” This conceptual framework delineates progressive intervention levels, providing a structured approach to understanding the diverse strategies available in longevity medicine. At the base of the Longevity Pyramid lies the level of prevention, emphasizing early detection strategies and advanced diagnostics or timely identification of potential health issues. Moving upwards, the next step involves lifestyle modifications, health-promoting behaviors, and proactive measures to delay the onset of age-related conditions. The Longevity Pyramid further explores the vast range of personalized interventions, highlighting the importance of tailoring medical approaches based on genetic predispositions, lifestyle factors, and unique health profiles, thereby optimizing interventions for maximal efficacy. These interventions aim to extend lifespan and reduce the impact and severity of age-related conditions, ensuring that additional years are characterized by vitality and wellbeing. By outlining these progressive levels of intervention, this review offers valuable insights into the evolving field of longevity medicine. This structured framework guides researchers and practitioners toward a nuanced strategic approach to advancing the science and practice of healthy aging.https://www.frontiersin.org/articles/10.3389/fragi.2024.1495029/fulllongevityhealthcareaginglifestylepreventive medicinepersonalized medicine |
| spellingShingle | Anđela Martinović Anđela Martinović Matilde Mantovani Matilde Mantovani Natalia Trpchevska Eva Novak Nikolay B. Milev Leonie Bode Collin Y. Ewald Evelyne Bischof Evelyne Bischof Tobias Reichmuth Rebecca Lapides Alexander Navarini Babak Saravi Elisabeth Roider Elisabeth Roider Elisabeth Roider Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity Frontiers in Aging longevity healthcare aging lifestyle preventive medicine personalized medicine |
| title | Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity |
| title_full | Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity |
| title_fullStr | Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity |
| title_full_unstemmed | Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity |
| title_short | Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity |
| title_sort | climbing the longevity pyramid overview of evidence driven healthcare prevention strategies for human longevity |
| topic | longevity healthcare aging lifestyle preventive medicine personalized medicine |
| url | https://www.frontiersin.org/articles/10.3389/fragi.2024.1495029/full |
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