Micellar Effects on Nucleophilic Addition Reaction and Applicability of Enzyme Catalysis Model
This study describes the effect of anionic and cationic micelles on nucleophilic addition reaction of rosaniline hydrochloride (RH) with hydroxide under pseudo-first order condition. Strong inhibitory effect is observed due to SDS micelle, whereas CTAB catalysed the reaction. This is explained on th...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2012/129436 |
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| author | R. K. London Singh |
| author_facet | R. K. London Singh |
| author_sort | R. K. London Singh |
| collection | DOAJ |
| description | This study describes the effect of anionic and cationic micelles on nucleophilic addition reaction of rosaniline hydrochloride (RH) with hydroxide under pseudo-first order condition. Strong inhibitory effect is observed due to SDS micelle, whereas CTAB catalysed the reaction. This is explained on the basis of electrostatic and hydrophobic interactions which are simultaneously operating in the reaction system. The kinetic data obtained is quantitatively analysed by applying the positive cooperativity model of enzyme catalysis. Binding constants and influence of counterions on the reaction have also been investigated. |
| format | Article |
| id | doaj-art-1a1c35e71c754f0cbf9e9cc3439f8ea1 |
| institution | OA Journals |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-1a1c35e71c754f0cbf9e9cc3439f8ea12025-08-20T02:01:58ZengWileyE-Journal of Chemistry0973-49452090-98102012-01-01931181118710.1155/2012/129436Micellar Effects on Nucleophilic Addition Reaction and Applicability of Enzyme Catalysis ModelR. K. London Singh0Department of Chemistry, D.M. College of Science, Imphal-795001, IndiaThis study describes the effect of anionic and cationic micelles on nucleophilic addition reaction of rosaniline hydrochloride (RH) with hydroxide under pseudo-first order condition. Strong inhibitory effect is observed due to SDS micelle, whereas CTAB catalysed the reaction. This is explained on the basis of electrostatic and hydrophobic interactions which are simultaneously operating in the reaction system. The kinetic data obtained is quantitatively analysed by applying the positive cooperativity model of enzyme catalysis. Binding constants and influence of counterions on the reaction have also been investigated.http://dx.doi.org/10.1155/2012/129436 |
| spellingShingle | R. K. London Singh Micellar Effects on Nucleophilic Addition Reaction and Applicability of Enzyme Catalysis Model E-Journal of Chemistry |
| title | Micellar Effects on Nucleophilic Addition Reaction and Applicability of Enzyme Catalysis Model |
| title_full | Micellar Effects on Nucleophilic Addition Reaction and Applicability of Enzyme Catalysis Model |
| title_fullStr | Micellar Effects on Nucleophilic Addition Reaction and Applicability of Enzyme Catalysis Model |
| title_full_unstemmed | Micellar Effects on Nucleophilic Addition Reaction and Applicability of Enzyme Catalysis Model |
| title_short | Micellar Effects on Nucleophilic Addition Reaction and Applicability of Enzyme Catalysis Model |
| title_sort | micellar effects on nucleophilic addition reaction and applicability of enzyme catalysis model |
| url | http://dx.doi.org/10.1155/2012/129436 |
| work_keys_str_mv | AT rklondonsingh micellareffectsonnucleophilicadditionreactionandapplicabilityofenzymecatalysismodel |