HMGA2 Promotes Cellular Proliferation, Invasion and Metastasis of Laryngeal Cancer Through TGF-β/Smad Signaling Pathway

HMGA2 Promotes Cellular Proliferation, Invasion and Metastasis of Laryngeal Cancer Through TGF-β/Smad Signaling Pathway

ObjectiveTo investigate the molecular mechanism by which HMGA2 participates in the TGF-β/Smad pathway in the regulation of the proliferation, aggression, and metastasis of laryngeal cancer. MethodsshRNA transfection was used to construct the HMGA2 knockdown laryngeal cancer TU686 cell model, and sub...

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Bibliographic Details
Main Authors: Xianxue WEN, Ruting LI, Xi WU, Renbin GUO, Jun WU, Lijuan MA
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2025-07-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
laryngeal cancer
tu686 cell
hmga2
tgf-β/smad
emt
Online Access:http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1216
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