VELYS robotic‐assisted total knee arthroplasty: Enhanced accuracy and comparable early outcomes versus manual instrumentation during adoption

Abstract Purpose This study assessed the accuracy and early clinical outcomes of the VELYS™ Robotic‐Assisted solution for total knee arthroplasty (TKA). Methods A multicenter, prospective non‐randomized 1:1 cohort study was conducted at five sites. Subjects underwent TKA with either manual instrumen...

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Main Authors: Timothy B. Alton, Erik P. Severson, Marcus C. Ford, James Lesko, Ian J. Leslie
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Journal of Experimental Orthopaedics
Subjects:
Online Access:https://doi.org/10.1002/jeo2.70163
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author Timothy B. Alton
Erik P. Severson
Marcus C. Ford
James Lesko
Ian J. Leslie
author_facet Timothy B. Alton
Erik P. Severson
Marcus C. Ford
James Lesko
Ian J. Leslie
author_sort Timothy B. Alton
collection DOAJ
description Abstract Purpose This study assessed the accuracy and early clinical outcomes of the VELYS™ Robotic‐Assisted solution for total knee arthroplasty (TKA). Methods A multicenter, prospective non‐randomized 1:1 cohort study was conducted at five sites. Subjects underwent TKA with either manual instrumentation or with robotic‐assistance (RA). RA procedures were the first conducted at each site, therefore, representing the adoption phase for each surgeon. Mechanical alignment was targeted in the manual arm, while the target and technique varied in the RA arm. The primary objective was a non‐inferiority (NI) analysis of the accuracy of the hip–knee–ankle (HKA) for RA versus manual, with a 1.5° NI margin. The accuracy of the mechanical medial distal femoral angle (mMDFA), mechanical medial proximal tibial angle (mMPTA) tibial posterior slope (TPS) angles were measured. Adverse events (AEs) and patient‐reported outcome measures (PROMs) were collected at 12 weeks and 1 year. Results One hundred participants were recruited for both manual and RA groups, the mean preoperative demographics and PROM scores were similar. The primary endpoint NI analysis was successful (p < 0.0001). The RA group demonstrated improved alignment accuracy of the femoral and tibial components compared to manual (mMDFA 1.3 vs. 1.9, p = 0.0026, mMPTA 1.2 vs. 1.5, p = 0.026, TPS 1.7 vs. 2.8, p < 0.0001). Serious AEs occurred in fewer RA subjects than in the manual (6 vs. 16, p = 0.040). Mean PROMs at 12 weeks and 1 year in the RA group compared to manual were either equivalent or improved (Forgotten Joint Score and pain at 12 weeks). Conclusions This study found that the RA system can be safely adopted without adversely impacting the long leg alignment or increasing the risk of complications. Further, it was observed that the accuracy of the femoral and tibial component positioning was improved, and there were positive trends in the rate of serious AEs and some PROMs at early follow‐up. Level of Evidence Level II.
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spelling doaj-art-1a0fffff3cea4f8898e6422dfb156cc42025-08-20T01:55:38ZengWileyJournal of Experimental Orthopaedics2197-11532025-01-01121n/an/a10.1002/jeo2.70163VELYS robotic‐assisted total knee arthroplasty: Enhanced accuracy and comparable early outcomes versus manual instrumentation during adoptionTimothy B. Alton0Erik P. Severson1Marcus C. Ford2James Lesko3Ian J. Leslie4Proliance Orthopedic Associates Renton Washington USAMinnesota Center for Orthopaedics Crosby Minnesota USACampbell Clinic Germantown Tennessee USADePuy Synthes Warsaw Indiana USADePuy Synthes Leeds UKAbstract Purpose This study assessed the accuracy and early clinical outcomes of the VELYS™ Robotic‐Assisted solution for total knee arthroplasty (TKA). Methods A multicenter, prospective non‐randomized 1:1 cohort study was conducted at five sites. Subjects underwent TKA with either manual instrumentation or with robotic‐assistance (RA). RA procedures were the first conducted at each site, therefore, representing the adoption phase for each surgeon. Mechanical alignment was targeted in the manual arm, while the target and technique varied in the RA arm. The primary objective was a non‐inferiority (NI) analysis of the accuracy of the hip–knee–ankle (HKA) for RA versus manual, with a 1.5° NI margin. The accuracy of the mechanical medial distal femoral angle (mMDFA), mechanical medial proximal tibial angle (mMPTA) tibial posterior slope (TPS) angles were measured. Adverse events (AEs) and patient‐reported outcome measures (PROMs) were collected at 12 weeks and 1 year. Results One hundred participants were recruited for both manual and RA groups, the mean preoperative demographics and PROM scores were similar. The primary endpoint NI analysis was successful (p < 0.0001). The RA group demonstrated improved alignment accuracy of the femoral and tibial components compared to manual (mMDFA 1.3 vs. 1.9, p = 0.0026, mMPTA 1.2 vs. 1.5, p = 0.026, TPS 1.7 vs. 2.8, p < 0.0001). Serious AEs occurred in fewer RA subjects than in the manual (6 vs. 16, p = 0.040). Mean PROMs at 12 weeks and 1 year in the RA group compared to manual were either equivalent or improved (Forgotten Joint Score and pain at 12 weeks). Conclusions This study found that the RA system can be safely adopted without adversely impacting the long leg alignment or increasing the risk of complications. Further, it was observed that the accuracy of the femoral and tibial component positioning was improved, and there were positive trends in the rate of serious AEs and some PROMs at early follow‐up. Level of Evidence Level II.https://doi.org/10.1002/jeo2.70163accuracycomparativelevel IIprospectiverobotic‐assistedVELYS
spellingShingle Timothy B. Alton
Erik P. Severson
Marcus C. Ford
James Lesko
Ian J. Leslie
VELYS robotic‐assisted total knee arthroplasty: Enhanced accuracy and comparable early outcomes versus manual instrumentation during adoption
Journal of Experimental Orthopaedics
accuracy
comparative
level II
prospective
robotic‐assisted
VELYS
title VELYS robotic‐assisted total knee arthroplasty: Enhanced accuracy and comparable early outcomes versus manual instrumentation during adoption
title_full VELYS robotic‐assisted total knee arthroplasty: Enhanced accuracy and comparable early outcomes versus manual instrumentation during adoption
title_fullStr VELYS robotic‐assisted total knee arthroplasty: Enhanced accuracy and comparable early outcomes versus manual instrumentation during adoption
title_full_unstemmed VELYS robotic‐assisted total knee arthroplasty: Enhanced accuracy and comparable early outcomes versus manual instrumentation during adoption
title_short VELYS robotic‐assisted total knee arthroplasty: Enhanced accuracy and comparable early outcomes versus manual instrumentation during adoption
title_sort velys robotic assisted total knee arthroplasty enhanced accuracy and comparable early outcomes versus manual instrumentation during adoption
topic accuracy
comparative
level II
prospective
robotic‐assisted
VELYS
url https://doi.org/10.1002/jeo2.70163
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