Primary orbital yolk sac tumor in an infant: A rare entity
We report a case of pure orbital yolk sac tumor (YST) in an 11-month-old infant, which is a rare entity. The child presented with progressive painless swelling of the right eye and on examination had proptosis, chemosis, and lid edema. Systemic examination was within normal limits. Magnetic resonanc...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-07-01
|
| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/IJPM.IJPM_741_21 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1825206059208278016 |
|---|---|
| author | Varsha Mishra Sandeep Jain Payal Malhotra Garima Durga Gauri Kapoor |
| author_facet | Varsha Mishra Sandeep Jain Payal Malhotra Garima Durga Gauri Kapoor |
| author_sort | Varsha Mishra |
| collection | DOAJ |
| description | We report a case of pure orbital yolk sac tumor (YST) in an 11-month-old infant, which is a rare entity. The child presented with progressive painless swelling of the right eye and on examination had proptosis, chemosis, and lid edema. Systemic examination was within normal limits. Magnetic resonance imaging (MRI) orbit revealed a lobulated heterogeneously enhancing right retroocular mass extending up to the orbital apex, displacing the optic nerve and eroding the medial orbital wall. Biopsy of the lesion revealed pure YST histology. Serum alpha-fetoprotein (AFP) was markedly raised at 76900 ng/mL. She was started on infant bleomycin etoposide cisplatin (BEP) chemotherapy protocol. There was a good clinical and radiological response. A high index of malignancy is required in young children presenting with orbital proptosis. A multidisciplinary approach and early intervention are essential to save both vision and life. |
| format | Article |
| id | doaj-art-1a0e0daf0e72462b884059ea5dfba554 |
| institution | Kabale University |
| issn | 0377-4929 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-1a0e0daf0e72462b884059ea5dfba5542025-02-07T13:37:58ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292023-07-0166365265410.4103/IJPM.IJPM_741_21Primary orbital yolk sac tumor in an infant: A rare entityVarsha MishraSandeep JainPayal MalhotraGarima DurgaGauri KapoorWe report a case of pure orbital yolk sac tumor (YST) in an 11-month-old infant, which is a rare entity. The child presented with progressive painless swelling of the right eye and on examination had proptosis, chemosis, and lid edema. Systemic examination was within normal limits. Magnetic resonance imaging (MRI) orbit revealed a lobulated heterogeneously enhancing right retroocular mass extending up to the orbital apex, displacing the optic nerve and eroding the medial orbital wall. Biopsy of the lesion revealed pure YST histology. Serum alpha-fetoprotein (AFP) was markedly raised at 76900 ng/mL. She was started on infant bleomycin etoposide cisplatin (BEP) chemotherapy protocol. There was a good clinical and radiological response. A high index of malignancy is required in young children presenting with orbital proptosis. A multidisciplinary approach and early intervention are essential to save both vision and life.https://journals.lww.com/10.4103/IJPM.IJPM_741_21germ cell tumorinfantmalignancyorbit |
| spellingShingle | Varsha Mishra Sandeep Jain Payal Malhotra Garima Durga Gauri Kapoor Primary orbital yolk sac tumor in an infant: A rare entity Indian Journal of Pathology and Microbiology germ cell tumor infant malignancy orbit |
| title | Primary orbital yolk sac tumor in an infant: A rare entity |
| title_full | Primary orbital yolk sac tumor in an infant: A rare entity |
| title_fullStr | Primary orbital yolk sac tumor in an infant: A rare entity |
| title_full_unstemmed | Primary orbital yolk sac tumor in an infant: A rare entity |
| title_short | Primary orbital yolk sac tumor in an infant: A rare entity |
| title_sort | primary orbital yolk sac tumor in an infant a rare entity |
| topic | germ cell tumor infant malignancy orbit |
| url | https://journals.lww.com/10.4103/IJPM.IJPM_741_21 |
| work_keys_str_mv | AT varshamishra primaryorbitalyolksactumorinaninfantarareentity AT sandeepjain primaryorbitalyolksactumorinaninfantarareentity AT payalmalhotra primaryorbitalyolksactumorinaninfantarareentity AT garimadurga primaryorbitalyolksactumorinaninfantarareentity AT gaurikapoor primaryorbitalyolksactumorinaninfantarareentity |