Vitamin D Deficiency in a Cohort of Neapolitan Pregnant Women: Do We Really Live in the City of the Sun?
Background: Insufficient serum 25-hydroxyvitamin D [25(OH)D] levels are a global public health issue, and pregnant women are a significant at-risk group. We aimed to assess maternal serum 25(OH)D concentrations in a cohort of Neapolitan pregnant women and the association with dietary habits, to defi...
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| Format: | Article |
| Language: | English |
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IMR Press
2023-03-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
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| Online Access: | https://www.imrpress.com/journal/CEOG/50/3/10.31083/j.ceog5003052 |
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| author | Laura Sarno Annunziata Carlea Serena Cabaro Carmen Imma Aquino Dalila Mantelli Giuseppe Perruolo Pietro Formisano Maurizio Guida Daniela Terracciano |
| author_facet | Laura Sarno Annunziata Carlea Serena Cabaro Carmen Imma Aquino Dalila Mantelli Giuseppe Perruolo Pietro Formisano Maurizio Guida Daniela Terracciano |
| author_sort | Laura Sarno |
| collection | DOAJ |
| description | Background: Insufficient serum 25-hydroxyvitamin D [25(OH)D] levels are a global public health issue, and pregnant women are a significant at-risk group. We aimed to assess maternal serum 25(OH)D concentrations in a cohort of Neapolitan pregnant women and the association with dietary habits, to define which patients are at increased risk of hypovitaminosis and how we can identify them. Methods: This was a prospective observational study. We included 103 pregnant women attending a routine third trimester obstetric examination. Information on obstetrical history and socio-demographic characteristics were obtained through interviews and medical records. Vitamin D intake was assessed using a food frequency questionnaire. Serum 25(OH)D concentration was measured by DiaSorin Liaison and the cut-off value for deficiency was set at 20 ng/mL. Results: Among the 103 pregnant women recruited, 71 (68.9%) were Vitamin D deficient (mean value 12.6 ± 0.5 ng/mL). No statistically significant differences were found between the women involved in the study for: maternal age, pre-pregnancy body mass index (BMI), gestational weight gain, and gestational age at investigation. Women with hypovitaminosis reported a significantly lower intake of milk/yoghurt, cheeses/dairy products and fish. Maternal hypovitaminosis D significantly correlated with low birth weight. Conclusions: Our study confirms that Vitamin D deficiency is a common finding also in sunny areas. Patients with low level of Vitamin D reported a lower intake of food rich of this micronutrient. An accurate anamnesis can be an easy way to identify pregnant women at risk of hypovitaminosis D for whom screening and supplementation can be suitable. |
| format | Article |
| id | doaj-art-1a01de06e34043d986809f1353cfe09b |
| institution | OA Journals |
| issn | 0390-6663 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj-art-1a01de06e34043d986809f1353cfe09b2025-08-20T02:01:58ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632023-03-015035210.31083/j.ceog5003052S0390-6663(22)01992-3Vitamin D Deficiency in a Cohort of Neapolitan Pregnant Women: Do We Really Live in the City of the Sun?Laura Sarno0Annunziata Carlea1Serena Cabaro2Carmen Imma Aquino3Dalila Mantelli4Giuseppe Perruolo5Pietro Formisano6Maurizio Guida7Daniela Terracciano8Department of Neurosciences, Reproductive Science and Dentistry, University of Naples Federico II, 80131 Naples, ItalyDepartment of Neurosciences, Reproductive Science and Dentistry, University of Naples Federico II, 80131 Naples, ItalyDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Gynecology and Obstetrics, University of Piemonte Orientale, Ospedale Maggiore della Carit\‘{a}, 28100 Novara, ItalyDepartment of Neurosciences, Reproductive Science and Dentistry, University of Naples Federico II, 80131 Naples, ItalyDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Neurosciences, Reproductive Science and Dentistry, University of Naples Federico II, 80131 Naples, ItalyDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, ItalyBackground: Insufficient serum 25-hydroxyvitamin D [25(OH)D] levels are a global public health issue, and pregnant women are a significant at-risk group. We aimed to assess maternal serum 25(OH)D concentrations in a cohort of Neapolitan pregnant women and the association with dietary habits, to define which patients are at increased risk of hypovitaminosis and how we can identify them. Methods: This was a prospective observational study. We included 103 pregnant women attending a routine third trimester obstetric examination. Information on obstetrical history and socio-demographic characteristics were obtained through interviews and medical records. Vitamin D intake was assessed using a food frequency questionnaire. Serum 25(OH)D concentration was measured by DiaSorin Liaison and the cut-off value for deficiency was set at 20 ng/mL. Results: Among the 103 pregnant women recruited, 71 (68.9%) were Vitamin D deficient (mean value 12.6 ± 0.5 ng/mL). No statistically significant differences were found between the women involved in the study for: maternal age, pre-pregnancy body mass index (BMI), gestational weight gain, and gestational age at investigation. Women with hypovitaminosis reported a significantly lower intake of milk/yoghurt, cheeses/dairy products and fish. Maternal hypovitaminosis D significantly correlated with low birth weight. Conclusions: Our study confirms that Vitamin D deficiency is a common finding also in sunny areas. Patients with low level of Vitamin D reported a lower intake of food rich of this micronutrient. An accurate anamnesis can be an easy way to identify pregnant women at risk of hypovitaminosis D for whom screening and supplementation can be suitable.https://www.imrpress.com/journal/CEOG/50/3/10.31083/j.ceog5003052vitamin dsun exposuredietary intakepregnancyobstetric outcomes |
| spellingShingle | Laura Sarno Annunziata Carlea Serena Cabaro Carmen Imma Aquino Dalila Mantelli Giuseppe Perruolo Pietro Formisano Maurizio Guida Daniela Terracciano Vitamin D Deficiency in a Cohort of Neapolitan Pregnant Women: Do We Really Live in the City of the Sun? Clinical and Experimental Obstetrics & Gynecology vitamin d sun exposure dietary intake pregnancy obstetric outcomes |
| title | Vitamin D Deficiency in a Cohort of Neapolitan Pregnant Women: Do We Really Live in the City of the Sun? |
| title_full | Vitamin D Deficiency in a Cohort of Neapolitan Pregnant Women: Do We Really Live in the City of the Sun? |
| title_fullStr | Vitamin D Deficiency in a Cohort of Neapolitan Pregnant Women: Do We Really Live in the City of the Sun? |
| title_full_unstemmed | Vitamin D Deficiency in a Cohort of Neapolitan Pregnant Women: Do We Really Live in the City of the Sun? |
| title_short | Vitamin D Deficiency in a Cohort of Neapolitan Pregnant Women: Do We Really Live in the City of the Sun? |
| title_sort | vitamin d deficiency in a cohort of neapolitan pregnant women do we really live in the city of the sun |
| topic | vitamin d sun exposure dietary intake pregnancy obstetric outcomes |
| url | https://www.imrpress.com/journal/CEOG/50/3/10.31083/j.ceog5003052 |
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