CD109, a master regulator of inflammatory responses

CD109, a master regulator of inflammatory responses

Inflammation is a complex response to harmful stimuli, crucial for immunity, and linked to chronic diseases and cancer, with TGF-β and NF-κB pathways as key regulators. CD109 is a glycosylphosphatidylinositol (GPI)-anchored protein, that our group has originally identified as a TGF-β co-receptor and...

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Bibliographic Details
Main Authors: Adel Batal, Setareh Garousi, Kenneth W. Finnson, Anie Philip
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
CD109
inflammatory response
TGF-β signaling
NF-κB signaling
pathway crosstalk
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1505008/full
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