Vitiligo detection capabilities of 1D photonic crystal biosensing design

Abstract This theoretical work focuses on the application of Tamm resonance-based biosensing using a one-dimensional photonic crystal for detecting skin vitiligo, a condition caused by the loss of pigment in the body. This biosensor utilizes the interaction of light with the photonic structure to id...

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Main Authors: Ali S. Alshomrany, Arafa H. Aly, B. A. Mohamed, S. Alamri, D. Mohamed, S K Awasthi, Zinab. S. Matar, A F Amin, H. Hanafy
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-83421-4
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author Ali S. Alshomrany
Arafa H. Aly
B. A. Mohamed
S. Alamri
D. Mohamed
S K Awasthi
Zinab. S. Matar
A F Amin
H. Hanafy
author_facet Ali S. Alshomrany
Arafa H. Aly
B. A. Mohamed
S. Alamri
D. Mohamed
S K Awasthi
Zinab. S. Matar
A F Amin
H. Hanafy
author_sort Ali S. Alshomrany
collection DOAJ
description Abstract This theoretical work focuses on the application of Tamm resonance-based biosensing using a one-dimensional photonic crystal for detecting skin vitiligo, a condition caused by the loss of pigment in the body. This biosensor utilizes the interaction of light with the photonic structure to identify the specific biomarkers associated with vitiligo. The proposed structure is composed of prism/Ag/skin-sample/(GaP/PS)N/glass. The MATLAB simulations are used to obtain numerical results pertaining to the work by using the transfer matrix method (TMM). The analysis of transmission spectra of the proposed structure shows its minute sensing ability of detecting skin vitiligo. The proposed sensor possesses a higher sensitivity of 1200 nm/RIU which is higher than the sensitivities of the sensor reported earlier. Moreover, the suggested biosensor possesses an extremely high-quality factor value of 40,650 with an exceptionally small full-width-half-maximum value of 0.04 nm.
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institution Kabale University
issn 2045-2322
language English
publishDate 2025-01-01
publisher Nature Portfolio
record_format Article
series Scientific Reports
spelling doaj-art-19f32bbdd6fc4f79a3e2f6035902057c2025-01-12T12:15:09ZengNature PortfolioScientific Reports2045-23222025-01-0115111210.1038/s41598-024-83421-4Vitiligo detection capabilities of 1D photonic crystal biosensing designAli S. Alshomrany0Arafa H. Aly1B. A. Mohamed2S. Alamri3D. Mohamed4S K Awasthi5Zinab. S. Matar6A F Amin7H. Hanafy8Department of Physics, College of Sciences, Umm Al-Qura UniversityPhysics Department, Faculty of Sciences, TH-PPM Group, Beni-Suef UniversityPhysics Department, Faculty of Sciences, TH-PPM Group, Beni-Suef UniversityDepartment of Mechanical Engineering, College of Engineering, King Khalid UniversityPhysics Department, Faculty of Sciences, TH-PPM Group, Beni-Suef UniversityDepartment of Physics and Material Science and Engineering, Jaypee Institute of Information TechnologyPhysics Department, College of Science, Umm Al-Qura UniversityFaculty of Technology and Education, Beni-Suef UniversityPhysics Department, Faculty of Sciences, TH-PPM Group, Beni-Suef UniversityAbstract This theoretical work focuses on the application of Tamm resonance-based biosensing using a one-dimensional photonic crystal for detecting skin vitiligo, a condition caused by the loss of pigment in the body. This biosensor utilizes the interaction of light with the photonic structure to identify the specific biomarkers associated with vitiligo. The proposed structure is composed of prism/Ag/skin-sample/(GaP/PS)N/glass. The MATLAB simulations are used to obtain numerical results pertaining to the work by using the transfer matrix method (TMM). The analysis of transmission spectra of the proposed structure shows its minute sensing ability of detecting skin vitiligo. The proposed sensor possesses a higher sensitivity of 1200 nm/RIU which is higher than the sensitivities of the sensor reported earlier. Moreover, the suggested biosensor possesses an extremely high-quality factor value of 40,650 with an exceptionally small full-width-half-maximum value of 0.04 nm.https://doi.org/10.1038/s41598-024-83421-4BiosensorPhotonic CrystalRefractive index (RI)SensitivityVitiligoSurface plasmon resonance (SPR).
spellingShingle Ali S. Alshomrany
Arafa H. Aly
B. A. Mohamed
S. Alamri
D. Mohamed
S K Awasthi
Zinab. S. Matar
A F Amin
H. Hanafy
Vitiligo detection capabilities of 1D photonic crystal biosensing design
Scientific Reports
Biosensor
Photonic Crystal
Refractive index (RI)
Sensitivity
Vitiligo
Surface plasmon resonance (SPR).
title Vitiligo detection capabilities of 1D photonic crystal biosensing design
title_full Vitiligo detection capabilities of 1D photonic crystal biosensing design
title_fullStr Vitiligo detection capabilities of 1D photonic crystal biosensing design
title_full_unstemmed Vitiligo detection capabilities of 1D photonic crystal biosensing design
title_short Vitiligo detection capabilities of 1D photonic crystal biosensing design
title_sort vitiligo detection capabilities of 1d photonic crystal biosensing design
topic Biosensor
Photonic Crystal
Refractive index (RI)
Sensitivity
Vitiligo
Surface plasmon resonance (SPR).
url https://doi.org/10.1038/s41598-024-83421-4
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