Top2b regulates morphological and migratory properties of retinal progenitor cells in vivo and upon transplantable matrix substrates

Top2b regulates morphological and migratory properties of retinal progenitor cells in vivo and upon transplantable matrix substrates

Aim: This study evaluated the impact of retinal extracellular matrix (ECM) and key biomaterial substrates on the motility of transplantable retinal cells with genomic manipulation, using the therapeutic molecule, Topoisomerase II beta (Top2b), as a model. Methods: Tests first applied in ovo electrop...

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Bibliographic Details
Main Authors: Alexandra C. Dabrowski, Alexandria R. Logan, Rameshwari Rayaji, Brianna Rodriguez, Li Cai, Maribel Vazquez
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2025-04-01
Series:Exploration of BioMat-X
Subjects:
icrf-193
ganglion cell layer
cadherins
collective motility
laminin
Online Access:https://www.explorationpub.com/uploads/Article/A101335/101335.pdf
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