Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman’s Disease

We present an interesting case of focal amyloidosis of the left breast which was intermixed with ductal carcinoma in situ (DCIS). On subsequent staging bilateral breast magnetic resonance imaging (MRI), the patient was found to have an additional suspicious enhancing mass with spiculated borders wit...

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Main Authors: David Chiang, Michael Lee, Pauline Germaine, Lydia Liao
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2013/190856
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author David Chiang
Michael Lee
Pauline Germaine
Lydia Liao
author_facet David Chiang
Michael Lee
Pauline Germaine
Lydia Liao
author_sort David Chiang
collection DOAJ
description We present an interesting case of focal amyloidosis of the left breast which was intermixed with ductal carcinoma in situ (DCIS). On subsequent staging bilateral breast magnetic resonance imaging (MRI), the patient was found to have an additional suspicious enhancing mass with spiculated borders within the left breast. This mass was biopsy proven to represent pleomorphic invasive lobular carcinoma. A pulmonary nodule within the lingula was also noted on the staging bilateral breast MRI and was biopsy proven to represent extranodal Castleman’s disease. Therefore, it is believed that our patient had secondary amyloidosis due to Castleman’s disease.
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institution Kabale University
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spelling doaj-art-19d05c89548e42a795bc0dd9356979452025-08-20T03:55:45ZengWileyCase Reports in Radiology2090-68622090-68702013-01-01201310.1155/2013/190856190856Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman’s DiseaseDavid Chiang0Michael Lee1Pauline Germaine2Lydia Liao3Department of Radiology, Cooper University Hospital, Camden, NJ 08103, USADepartment of Radiology, Cooper University Hospital, Camden, NJ 08103, USADepartment of Radiology, Cooper University Hospital, Camden, NJ 08103, USADepartment of Radiology, Cooper University Hospital, Camden, NJ 08103, USAWe present an interesting case of focal amyloidosis of the left breast which was intermixed with ductal carcinoma in situ (DCIS). On subsequent staging bilateral breast magnetic resonance imaging (MRI), the patient was found to have an additional suspicious enhancing mass with spiculated borders within the left breast. This mass was biopsy proven to represent pleomorphic invasive lobular carcinoma. A pulmonary nodule within the lingula was also noted on the staging bilateral breast MRI and was biopsy proven to represent extranodal Castleman’s disease. Therefore, it is believed that our patient had secondary amyloidosis due to Castleman’s disease.http://dx.doi.org/10.1155/2013/190856
spellingShingle David Chiang
Michael Lee
Pauline Germaine
Lydia Liao
Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman’s Disease
Case Reports in Radiology
title Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman’s Disease
title_full Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman’s Disease
title_fullStr Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman’s Disease
title_full_unstemmed Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman’s Disease
title_short Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman’s Disease
title_sort amyloidosis of the breast with multicentric dcis and pleomorphic invasive lobular carcinoma in a patient with underlying extranodal castleman s disease
url http://dx.doi.org/10.1155/2013/190856
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