Inhaling arsenic aggravates airway hyperreactivity by upregulating PNEC-sourced 5-HT in OVA-induced allergic asthma

Inhaling arsenic aggravates airway hyperreactivity by upregulating PNEC-sourced 5-HT in OVA-induced allergic asthma

Increasing epidemiological evidence has proved that early-life exposure to inorganic arsenic (As) elevates the risks of childhood asthma. The present research aimed to explore susceptibility of respiratory As exposure to allergic asthma in a mouse model. BALB/c mice on postnatal day (PND) 28 were ex...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xue Lu, Zhu-Xia Tan, Ya-Xin Yao, Ze-Yan Li, Yan-Yan Zhu, Qian-Qun Yang, Zhao Li, Kun Peng, Yan Wang, De-Xiang Xu
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Series:	Ecotoxicology and Environmental Safety
Subjects:	Arsenic Respiratory tract Allergic asthma Airway hyperreactivity Pulmonary neuroendocrine cell 5-hydroxytryptamine
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651325001009
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

PLIN5 contributes to lipophagy of hepatic stellate cells induced by inorganic arsenic
by: Haomiao Li, et al.
Published: (2025-01-01)

The Impact of Adequate Selenium Intake on Severity Symptoms and Quality of Life among People with Allergic Rhinitis
by: Thanyapron Tiyawisutsri, et al.
Published: (2025-02-01)

Two types of vidian neurectomy show efficacy in treating allergic rhinitis and vasomotor rhinitis
by: ShuJuan Sun, et al.
Published: (2024-11-01)

Advanced graphene oxide synthesis for arsenic removal from groundwater in Mexico and Colombia
by: J.P. Rodríguez-Caicedo, et al.
Published: (2025-03-01)

Short-term association between ambient air pollution and childhood non-allergic rhinitis: A time-series study at a National Children's Regional Medical Center, in Hefei, China, from 2015 to 2021
by: Wei Cui, et al.
Published: (2025-01-01)

Urinary concentrations of arsenic species in older Dutch adults and risk of chronic kidney disease
by: Hannah P. McKeon, et al.
Published: (2025-02-01)

Field-scale screening of pumpkin cultivars for cost-effectiveness of “repairing while producing” in cadmium-arsenic co-contaminated agricultural land
by: Xingxiu Huang, et al.
Published: (2025-01-01)

Protective and anti-inflammatory effects of caffeic acid phenethyl ester on arsenic-induced vasculitis in vivo
by: Yasser Kofiah, et al.
Published: (2025-02-01)

Haematological, Liver Function Parameters and Heavy Metal Assessment of KWMC Workers at Roadside and Mixed Waste Dumpsites in Kwara State, Nigeria
by: D.T. Ogundele, et al.
Published: (2019-08-01)

MECHANISMS AND CLINICAL PERSPECTIVES OF ALLERGEN-SPECIFIC IMMUNOTHERAPY
by: Leila Akhvlediani, et al.
Published: (2024-12-01)

Extracellular electron shuttles induced transformation and mobilization of Fe/As with the occurrence of biogenic vivianite
by: Jia Wang, et al.
Published: (2025-01-01)

MSCs with upregulated lipid metabolism block hematopoietic stem cell differentiation via exosomal CTP-1A in MDS
by: Chunlai Yin, et al.
Published: (2025-02-01)

Biphasic anaphylaxis in a Canadian tertiary care centre: an evaluation of incidence and risk factors from electronic health records and telephone interviews
by: Anne K. Ellis, et al.
Published: (2025-02-01)

Rapid detection of Tulipalin A with SESI-Orbitrap MS: an exploration across spring flowers
by: An N. T. Phan, et al.
Published: (2025-02-01)

Keratoconus with two consecutive re-emergences: a case report
by: Peicheng Zhang, et al.
Published: (2025-02-01)

Anti-allergic potentials of Ceriops decandra leaves in TDI-induced allergic mice: Comprehensive in-vivo and in-silico studies
by: Aishwarja Dey, et al.
Published: (2025-02-01)

RTEL1 is upregulated in gastric cancer and promotes tumor growth
by: Chunyu Yang, et al.
Published: (2024-12-01)

Primary care management of allergic rhinitis in children
by: Amanda Loke, et al.
Published: (2024-09-01)

Pesticide Toxicity Profile: Arsenical Herbicides
by: Frederick Fishel
Published: (2019-05-01)

The clinical characteristics and implications of acute kidney injury during induction therapy for acute promyelocytic leukemia
by: Kai Shen, et al.
Published: (2025-02-01)

Follistatin like-1 aggravates silica-induced mouse lung injury
by: Yinshan Fang, et al.
Published: (2017-03-01)

ATP1B3 may promote glioma proliferation and migration through MAPK/NF-KB signaling pathway
by: Qikang Yan, et al.
Published: (2025-02-01)

Editorial: T and B cell immune dynamics in allergic response
by: Mrinmoy Das, et al.
Published: (2025-02-01)

Vehicle-routing problem for low-carbon cold chain logistics based on the idea of cost–benefit
by: Yan Liu, et al.
Published: (2025-01-01)

Transport and Mitigation of Exhaled Electronic Cigarette Aerosols in a Multizone Indoor Environment
by: Li Zhang, et al.
Published: (2020-05-01)

Cuproptosis genes in predicting the occurrence of allergic rhinitis and pharmacological treatment.
by: Ting Yi
Published: (2025-01-01)

Cuproptosis genes in predicting the occurrence of allergic rhinitis and pharmacological treatment
by: Ting Yi
Published: (2025-01-01)

Effects of dietary chlorogenic acid supplementation on laying performance, egg quality, antioxidant capacity, and liver lipid metabolism in late-peak laying hens
by: Haitong Zhao, et al.
Published: (2025-12-01)

Lead-induced actin polymerization aggravates neutrophil extracellular trap formation and contributes to vascular inflammation
by: Qiying Nong, et al.
Published: (2025-01-01)

Attenuation processes in positive social emotion upregulation: Disentangling functional role of ventrolateral prefrontal cortex
by: Dmitriy D. Bezmaternykh, et al.
Published: (2025-02-01)

Treatment Preferences for Acute Allergic Reactions: A Discrete Choice Experiment
by: Sofia Löfvendahl, et al.
Published: (2024-06-01)

HAG1 Regulates Arsenic Allocation and Accumulation in Rice Grains
by: Yang Huan, et al.
Published: (2025-01-01)

Sulfur-vulcanized CoFe2O4 with high-efficiency photo-to-thermal conversion for enhanced CO2 reduction and mechanistic insights into selectivity
by: Xiaoke Chen, et al.
Published: (2025-03-01)

A data-driven modeling method for secondary frequency regulation characteristic of thermal power units
by: LI Zhijun, et al.
Published: (2025-01-01)

Influence of sulfur and selenium application on wheat growth in arsenic-contaminated soil
by: Huan Luo, et al.
Published: (2025-01-01)

Regulatory mechanism of exogenous myo-inositol improving high temperature stress tolerance of tomato seedlings
by: CHEN Yan, et al.
Published: (2024-12-01)

Roxadustat improves diabetic myocardial injury by upregulating HIF-1α/UCP2 against oxidative stress
by: Tingting Fang, et al.
Published: (2025-02-01)

Celastrol promotes DNA damage and apoptosis in uterine corpus endometrial carcinoma via promotion of KAT2B-mediated RBPJ acetylation and repression of MCM4 transcription
by: Lipeng Pei, et al.
Published: (2025-02-01)

Tunnel face stability in strata rich in water with soft upper and hard lower layers
by: Tao Zhan, et al.
Published: (2025-02-01)

Plasma myeloperoxidase interactions with cadmium, lead, arsenic, and selenium and their impact on chronic kidney disease
by: Hsi-Hsien Chen, et al.
Published: (2025-01-01)