Clinical trial landscape of gene therapy for retinal degenerative diseases: an analysis based on the Trialtrove database
Abstract Gene therapy has changed the way retinal degenerative diseases are explored and treated. Analyzing past and ongoing clinical trials using gene therapy for retinal degenerative diseases will provide important insight into academic, medical, and other communities. This study retrospectively a...
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| Format: | Article |
| Language: | English |
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BMC
2025-05-01
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| Series: | Stem Cell Research & Therapy |
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| Online Access: | https://doi.org/10.1186/s13287-025-04387-2 |
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| author | Shizhou Cheng Chuyun Xing Zijian Chen Shu Zhang Wanghao Chen |
| author_facet | Shizhou Cheng Chuyun Xing Zijian Chen Shu Zhang Wanghao Chen |
| author_sort | Shizhou Cheng |
| collection | DOAJ |
| description | Abstract Gene therapy has changed the way retinal degenerative diseases are explored and treated. Analyzing past and ongoing clinical trials using gene therapy for retinal degenerative diseases will provide important insight into academic, medical, and other communities. This study retrospectively analyzed 209 clinical trials in the Trialtrove database initiated before 2025. |
| format | Article |
| id | doaj-art-19c3ef01b3634edfadabbb3d61862b4c |
| institution | OA Journals |
| issn | 1757-6512 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Stem Cell Research & Therapy |
| spelling | doaj-art-19c3ef01b3634edfadabbb3d61862b4c2025-08-20T02:39:03ZengBMCStem Cell Research & Therapy1757-65122025-05-011611410.1186/s13287-025-04387-2Clinical trial landscape of gene therapy for retinal degenerative diseases: an analysis based on the Trialtrove databaseShizhou Cheng0Chuyun Xing1Zijian Chen2Shu Zhang3Wanghao Chen4Department of Ophthalmology, The First Affiliated Hospital of Yangtze UniversityDepartment of Pain Management, The First Affiliated Hospital of Yangtze UniversityDepartment of Ophthalmology, The First Affiliated Hospital of Yangtze UniversityDepartment of Ophthalmology, The First Affiliated Hospital of Yangtze UniversityDepartment of Ophthalmology, The First Affiliated Hospital of Yangtze UniversityAbstract Gene therapy has changed the way retinal degenerative diseases are explored and treated. Analyzing past and ongoing clinical trials using gene therapy for retinal degenerative diseases will provide important insight into academic, medical, and other communities. This study retrospectively analyzed 209 clinical trials in the Trialtrove database initiated before 2025.https://doi.org/10.1186/s13287-025-04387-2Gene therapyClinical trialRetinal degenerative diseasesOphthalmic treatment |
| spellingShingle | Shizhou Cheng Chuyun Xing Zijian Chen Shu Zhang Wanghao Chen Clinical trial landscape of gene therapy for retinal degenerative diseases: an analysis based on the Trialtrove database Stem Cell Research & Therapy Gene therapy Clinical trial Retinal degenerative diseases Ophthalmic treatment |
| title | Clinical trial landscape of gene therapy for retinal degenerative diseases: an analysis based on the Trialtrove database |
| title_full | Clinical trial landscape of gene therapy for retinal degenerative diseases: an analysis based on the Trialtrove database |
| title_fullStr | Clinical trial landscape of gene therapy for retinal degenerative diseases: an analysis based on the Trialtrove database |
| title_full_unstemmed | Clinical trial landscape of gene therapy for retinal degenerative diseases: an analysis based on the Trialtrove database |
| title_short | Clinical trial landscape of gene therapy for retinal degenerative diseases: an analysis based on the Trialtrove database |
| title_sort | clinical trial landscape of gene therapy for retinal degenerative diseases an analysis based on the trialtrove database |
| topic | Gene therapy Clinical trial Retinal degenerative diseases Ophthalmic treatment |
| url | https://doi.org/10.1186/s13287-025-04387-2 |
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