Antimicrobial and Antiradical Activity of Extracts from Leaves of Various Cultivars of <i>Pyrus communis</i> and <i>Pyrus pyrifolia</i>
Certain plant raw materials are rich in antioxidant and antimicrobial compounds, which are highly valued in modern medicine. These include the leaves of various species and cultivars of pears. For our research, we chose the leaves of the common pear (<i>Pyrus communis</i>) and Asian pear...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-06-01
|
| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/15/6/821 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849431894219816960 |
|---|---|
| author | Beata Żbikowska Magdalena Kotowska Andrzej Gamian Katarzyna Patek Katarzyna Matuła Daria Augustyniak Kamila Korzekwa Zbigniew Sroka |
| author_facet | Beata Żbikowska Magdalena Kotowska Andrzej Gamian Katarzyna Patek Katarzyna Matuła Daria Augustyniak Kamila Korzekwa Zbigniew Sroka |
| author_sort | Beata Żbikowska |
| collection | DOAJ |
| description | Certain plant raw materials are rich in antioxidant and antimicrobial compounds, which are highly valued in modern medicine. These include the leaves of various species and cultivars of pears. For our research, we chose the leaves of the common pear (<i>Pyrus communis</i>) and Asian pear (<i>Pyrus pyrifolia</i>). Four different extracts were obtained from all raw materials and were investigated for their antimicrobial and antioxidant activity. The content of total phenolics and flavonoids was measured using colorimetric methods, and antiradical activity was measured using DPPH and ABTS radical probes. The antimicrobial activity of extracts was measured using the disc diffusion method, and the amount of major antimicrobial components (hydroquinone and arbutin) was measured using the HPLC method. The highest amount of general phenols and flavonoids was found in ethyl acetate extracts in all cultivars, and the lowest amount of phenols was found in the remaining aqueous solution. The amount of general phenols positively correlated with the antiradical activity of extracts. The strongest antimicrobial activity against Gram-positive and Gram-negative pathogens corresponded to the highest content of hydroquinone and arbutin in ethyl acetate extracts. Extracts obtained from pear leaves showed an average content of phenolic compounds and average antiradical activity compared to extracts from other raw materials, especially green tea or bergenia leaves. The amount of hydroquinone was moderate, lower than that of arbutin. The antimicrobial activity of the extracts was moderate due to the average amount of hydroquinone, which is the main antimicrobial compound. |
| format | Article |
| id | doaj-art-19bf84724d904d4a8d83d1cbff6ff776 |
| institution | Kabale University |
| issn | 2218-273X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj-art-19bf84724d904d4a8d83d1cbff6ff7762025-08-20T03:27:29ZengMDPI AGBiomolecules2218-273X2025-06-0115682110.3390/biom15060821Antimicrobial and Antiradical Activity of Extracts from Leaves of Various Cultivars of <i>Pyrus communis</i> and <i>Pyrus pyrifolia</i>Beata Żbikowska0Magdalena Kotowska1Andrzej Gamian2Katarzyna Patek3Katarzyna Matuła4Daria Augustyniak5Kamila Korzekwa6Zbigniew Sroka7Department of Pharmacognosy and Herbal Medicine, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, PolandLaboratory of Molecular Biology of Microorganisms, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Rudolfa Weigla 12, 53-114 Wrocław, PolandDepartment of Immunology of Infectious Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Rudolfa Weigla 12, 53-114 Wrocław, PolandFaculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, PolandFaculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, PolandDepartment of Pathogen Biology and Immunology, University of Wroclaw, S. Przybyszewskiego 63, 51-148 Wrocław, PolandDepartment of Microbiology, University of Wroclaw, S. Przybyszewskiego 63, 51-148 Wrocław, PolandDepartment of Pharmacognosy and Herbal Medicine, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, PolandCertain plant raw materials are rich in antioxidant and antimicrobial compounds, which are highly valued in modern medicine. These include the leaves of various species and cultivars of pears. For our research, we chose the leaves of the common pear (<i>Pyrus communis</i>) and Asian pear (<i>Pyrus pyrifolia</i>). Four different extracts were obtained from all raw materials and were investigated for their antimicrobial and antioxidant activity. The content of total phenolics and flavonoids was measured using colorimetric methods, and antiradical activity was measured using DPPH and ABTS radical probes. The antimicrobial activity of extracts was measured using the disc diffusion method, and the amount of major antimicrobial components (hydroquinone and arbutin) was measured using the HPLC method. The highest amount of general phenols and flavonoids was found in ethyl acetate extracts in all cultivars, and the lowest amount of phenols was found in the remaining aqueous solution. The amount of general phenols positively correlated with the antiradical activity of extracts. The strongest antimicrobial activity against Gram-positive and Gram-negative pathogens corresponded to the highest content of hydroquinone and arbutin in ethyl acetate extracts. Extracts obtained from pear leaves showed an average content of phenolic compounds and average antiradical activity compared to extracts from other raw materials, especially green tea or bergenia leaves. The amount of hydroquinone was moderate, lower than that of arbutin. The antimicrobial activity of the extracts was moderate due to the average amount of hydroquinone, which is the main antimicrobial compound.https://www.mdpi.com/2218-273X/15/6/821pear leaf extractsarbutinhydroquinonephenolic compoundsantibacterial activityantioxidant activity |
| spellingShingle | Beata Żbikowska Magdalena Kotowska Andrzej Gamian Katarzyna Patek Katarzyna Matuła Daria Augustyniak Kamila Korzekwa Zbigniew Sroka Antimicrobial and Antiradical Activity of Extracts from Leaves of Various Cultivars of <i>Pyrus communis</i> and <i>Pyrus pyrifolia</i> Biomolecules pear leaf extracts arbutin hydroquinone phenolic compounds antibacterial activity antioxidant activity |
| title | Antimicrobial and Antiradical Activity of Extracts from Leaves of Various Cultivars of <i>Pyrus communis</i> and <i>Pyrus pyrifolia</i> |
| title_full | Antimicrobial and Antiradical Activity of Extracts from Leaves of Various Cultivars of <i>Pyrus communis</i> and <i>Pyrus pyrifolia</i> |
| title_fullStr | Antimicrobial and Antiradical Activity of Extracts from Leaves of Various Cultivars of <i>Pyrus communis</i> and <i>Pyrus pyrifolia</i> |
| title_full_unstemmed | Antimicrobial and Antiradical Activity of Extracts from Leaves of Various Cultivars of <i>Pyrus communis</i> and <i>Pyrus pyrifolia</i> |
| title_short | Antimicrobial and Antiradical Activity of Extracts from Leaves of Various Cultivars of <i>Pyrus communis</i> and <i>Pyrus pyrifolia</i> |
| title_sort | antimicrobial and antiradical activity of extracts from leaves of various cultivars of i pyrus communis i and i pyrus pyrifolia i |
| topic | pear leaf extracts arbutin hydroquinone phenolic compounds antibacterial activity antioxidant activity |
| url | https://www.mdpi.com/2218-273X/15/6/821 |
| work_keys_str_mv | AT beatazbikowska antimicrobialandantiradicalactivityofextractsfromleavesofvariouscultivarsofipyruscommunisiandipyruspyrifoliai AT magdalenakotowska antimicrobialandantiradicalactivityofextractsfromleavesofvariouscultivarsofipyruscommunisiandipyruspyrifoliai AT andrzejgamian antimicrobialandantiradicalactivityofextractsfromleavesofvariouscultivarsofipyruscommunisiandipyruspyrifoliai AT katarzynapatek antimicrobialandantiradicalactivityofextractsfromleavesofvariouscultivarsofipyruscommunisiandipyruspyrifoliai AT katarzynamatuła antimicrobialandantiradicalactivityofextractsfromleavesofvariouscultivarsofipyruscommunisiandipyruspyrifoliai AT dariaaugustyniak antimicrobialandantiradicalactivityofextractsfromleavesofvariouscultivarsofipyruscommunisiandipyruspyrifoliai AT kamilakorzekwa antimicrobialandantiradicalactivityofextractsfromleavesofvariouscultivarsofipyruscommunisiandipyruspyrifoliai AT zbigniewsroka antimicrobialandantiradicalactivityofextractsfromleavesofvariouscultivarsofipyruscommunisiandipyruspyrifoliai |