Anaplasma phagocytophilum AFAP targets the host nucleolus and inhibits induced apoptosis

Anaplasma phagocytophilum AFAP targets the host nucleolus and inhibits induced apoptosis

Anaplasma phagocytophilum, the etiologic agent of human granulocytic anaplasmosis (HGA), is an obligate intracellular Gram-negative bacterium. During infection, A. phagocytophilum transfers its type IV secretion system (T4SS) effector proteins into host cells to manipulate cellular processes. AFAP (...

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Bibliographic Details
Main Authors: Daxiu Zhang, Lifeng Yu, Hui Tang, Hua Niu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Microbiology
Subjects:
Anaplasma phagocytophilum
type IV secretion system
proteomic analysis
apoptosis
nucleolus
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1533640/full
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