CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Abstract The damage of blood spinal cord barrier (BSCB) is contributing to the disruption of immune microenvironment within central nervous system during the progression of multiple sclerosis (MS) and experimental allergic encephalomyelitis (EAE). Nevertheless, the underlying mechanisms responsible...

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Bibliographic Details
Main Authors: Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
autophagy
blood spinal cord barriers
CXCL13
experimental allergic encephalomyelitis
multiple sclerosis
RNF6
Online Access:https://doi.org/10.1002/advs.202414550
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https://doi.org/10.1002/advs.202414550

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