Endothelial activation markers (VCAM-1, vWF) in patients with chronic hepatitis C and insulin resistance
Blood markers of endothelial activation (sVCAM-1, vWF: Ag) in patients with chronic hepatitis C in the presence of insulin resistance, metabolic syndrome and its components had been evaluated. The study included 69 patients with chronic hepatitis C with oligosymptomatic the disease. In one third of...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2014-09-01
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| Series: | Журнал инфектологии |
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| Online Access: | https://journal.niidi.ru/jofin/article/view/132 |
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| author | T. V. Antonova M. A. Romanova Yu. V. Lymar |
| author_facet | T. V. Antonova M. A. Romanova Yu. V. Lymar |
| author_sort | T. V. Antonova |
| collection | DOAJ |
| description | Blood markers of endothelial activation (sVCAM-1, vWF: Ag) in patients with chronic hepatitis C in the presence of insulin resistance, metabolic syndrome and its components had been evaluated. The study included 69 patients with chronic hepatitis C with oligosymptomatic the disease. In one third of cases of chronic hepatitis C (33.3%) showed improvement in the blood content of sVCAM-1 and / or vWF: Ag. In patients with chronic hepatitis C with insulin resistance, metabolic syndrome significantly more often found signs adhesion of endothelial dysfunction (increased blood concentrations of sVCAM-1) than in patients without these disorders. Found that in patients with severe hepatic fibrosis in patients with chronic hepatitis C blood concentration sVCAM-1 is significantly higher compared to patients with early stages of fibrosis (F0-F2), including those in patients without insulin resistance. These data suggest the multivariate development of endothelial dysfunction in chronic hepatitis C. |
| format | Article |
| id | doaj-art-19addc65e364426b89d10f76bd90e27f |
| institution | Kabale University |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2014-09-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-19addc65e364426b89d10f76bd90e27f2025-08-20T03:44:24ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0144465110.22625/2072-6732-2012-4-4-46-51146Endothelial activation markers (VCAM-1, vWF) in patients with chronic hepatitis C and insulin resistanceT. V. Antonova0M. A. Romanova1Yu. V. Lymar2Saint-Petersburg State Medical University named after academic I.P. Pavlov, Saint-Petersburg Federal Centre of Heart, Blood and Endocrinology named after V.A. Almazov, Saint-PetersburgSaint-Petersburg State Medical University named after academic I.P. Pavlov, Saint-PetersburgFederal Centre of Heart, Blood and Endocrinology named after V.A. Almazov, Saint-PetersburgBlood markers of endothelial activation (sVCAM-1, vWF: Ag) in patients with chronic hepatitis C in the presence of insulin resistance, metabolic syndrome and its components had been evaluated. The study included 69 patients with chronic hepatitis C with oligosymptomatic the disease. In one third of cases of chronic hepatitis C (33.3%) showed improvement in the blood content of sVCAM-1 and / or vWF: Ag. In patients with chronic hepatitis C with insulin resistance, metabolic syndrome significantly more often found signs adhesion of endothelial dysfunction (increased blood concentrations of sVCAM-1) than in patients without these disorders. Found that in patients with severe hepatic fibrosis in patients with chronic hepatitis C blood concentration sVCAM-1 is significantly higher compared to patients with early stages of fibrosis (F0-F2), including those in patients without insulin resistance. These data suggest the multivariate development of endothelial dysfunction in chronic hepatitis C.https://journal.niidi.ru/jofin/article/view/132chronic hepatitis cinsulin resistancevascular cellular adhesion molecule-1von willebrand factor |
| spellingShingle | T. V. Antonova M. A. Romanova Yu. V. Lymar Endothelial activation markers (VCAM-1, vWF) in patients with chronic hepatitis C and insulin resistance Журнал инфектологии chronic hepatitis c insulin resistance vascular cellular adhesion molecule-1 von willebrand factor |
| title | Endothelial activation markers (VCAM-1, vWF) in patients with chronic hepatitis C and insulin resistance |
| title_full | Endothelial activation markers (VCAM-1, vWF) in patients with chronic hepatitis C and insulin resistance |
| title_fullStr | Endothelial activation markers (VCAM-1, vWF) in patients with chronic hepatitis C and insulin resistance |
| title_full_unstemmed | Endothelial activation markers (VCAM-1, vWF) in patients with chronic hepatitis C and insulin resistance |
| title_short | Endothelial activation markers (VCAM-1, vWF) in patients with chronic hepatitis C and insulin resistance |
| title_sort | endothelial activation markers vcam 1 vwf in patients with chronic hepatitis c and insulin resistance |
| topic | chronic hepatitis c insulin resistance vascular cellular adhesion molecule-1 von willebrand factor |
| url | https://journal.niidi.ru/jofin/article/view/132 |
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