Novel Presentation of Type 1 Wolfram Syndrome as Intracranial Hemorrhage and Longitudinally Extensive Transverse Myelitis: Neuroimaging and Angiographic Findings

Novel Presentation of Type 1 Wolfram Syndrome as Intracranial Hemorrhage and Longitudinally Extensive Transverse Myelitis: Neuroimaging and Angiographic Findings

Wolfram syndrome (WS), a rare genetic neurodegenerative condition, is primarily characterized by diabetes mellitus, optic atrophy, diabetes insipidus, and sensorineural hearing loss, along with diverse systemic manifestations. Late-stage cases exhibit widespread brain atrophy. While bleeding tendenc...

Full description

Saved in:
Bibliographic Details
Main Authors: Ravi P Singh, SS Jayanth, KT Seetam, Vikram V Holla, HR Arvinda, M Netravathi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-03-01
Series:Annals of Indian Academy of Neurology
Subjects:
didmoad
intracranial bleeding
wolfram syndrome
Online Access:https://journals.lww.com/10.4103/aian.aian_613_24
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Wolfram syndrome (WS), a rare genetic neurodegenerative condition, is primarily characterized by diabetes mellitus, optic atrophy, diabetes insipidus, and sensorineural hearing loss, along with diverse systemic manifestations. Late-stage cases exhibit widespread brain atrophy. While bleeding tendencies are not commonly observed in Type 2 WS (WS2), there is a distinctive bleeding tendency that is exclusive to WS2, with no documented occurrences in Type 1 WS (WS1). Extensive documentation exists regarding various neurologic manifestations of this syndrome; however, as of now, there is no reported mention of intracranial hemorrhage, a rarity within this condition.
ISSN:0972-2327
1998-3549

Similar Items