Dis3l2 is essential for neural crest survival by modulating Akt signaling

Abstract DIS3-like 3’-5’ exoribonuclease 2 (DIS3L2), an exoribonuclease, is known to preferentially degrade uridylated RNA substrates, miRNAs, and ncRNAs. Recent reports show that DIS3L2 also plays a key role in cell proliferation and tumor growth. Mutations in DIS3L2 are associated with congenital...

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Bibliographic Details
Main Authors: Sian D’Silva, Tuhina Prasad, Megha Kumar
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cell Communication and Signaling
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Online Access:https://doi.org/10.1186/s12964-025-02288-8
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