Positive Charge in an Antimalarial Compound Unlocks Broad-Spectrum Antibacterial Activity

Positive Charge in an Antimalarial Compound Unlocks Broad-Spectrum Antibacterial Activity

Saved in:

Bibliographic Details
Main Authors:	Maria Braun-Cornejo, Mitchell Platteschorre, Vincent de Vries, Patricia Bravo, Vidhisha Sonawane, Mostafa M. Hamed, Jörg Haupenthal, Norbert Reiling, Matthias Rottmann, Dennis Piet, Peter Maas, Eleonora Diamanti, Anna K. H. Hirsch
Format:	Article
Language:	English
Published:	American Chemical Society 2025-02-01
Series:	JACS Au
Online Access:	https://doi.org/10.1021/jacsau.4c00935
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Unlocking the antimalarial potential of novel steroid-tetraoxane hybrids through consensus molecular docking and molecular dynamics investigation
by: Dipankar Nath, et al.
Published: (2025-08-01)

The Importance of Murine Models in Determining In Vivo Pharmacokinetics, Safety, and Efficacy in Antimalarial Drug Discovery
by: Glory Adebayo, et al.
Published: (2025-03-01)

How to tackle antimalarial resistance?
by: Didier Leroy
Published: (2016-12-01)

Isolation and validation of antimalarial compounds from Phyllanthus emblica leaves for new antimalarial drug development
by: Selvam Naveenkumar, et al.
Published: (2025-05-01)

THE TRAGEDY CAUSED BY FAKE ANTIMALARIAL DRUGS
by: Pierre Ambroise-Thomas
Published: (2012-01-01)

Antimalarial Herbal Plants in Kupang, Indonesia
by: Ihwan Ihwan, et al.
Published: (2017-04-01)

THE TRAGEDY CAUSED BY FAKE ANTIMALARIAL DRUGS
by: Pierre Ambroise-Thomas
Published: (2012-05-01)

An Alternative Paradigm for the Role of Antimalarial Plants in Africa
by: Steven Maranz
Published: (2012-01-01)

Prescribing trend of antimalarial drugs at the Ghana Police Hospital
by: Daniel Kwame Afriyie, et al.
Published: (2015-04-01)

Unravelling the mode of action of the Tres Cantos Antimalarial Set (TCAMS): investigating the mechanism of potent antimalarial compounds potentially targeting the human serotonin receptor
by: Benedito Matheus dos Santos, et al.
Published: (2025-02-01)

Assessing the rise in broad-based inflationary pressure during 2021 and 2022
by: Taylor Mitchell, et al.
Published: (2023-02-01)

Antimalarial Drug Repurposing of Epirubicin and Pelitinib in Combination with Artemether and Lumefantrine
by: Douglas O. Ochora, et al.
Published: (2025-06-01)

In silico Evaluation of the Antimalarial Potential of the Phytoconstituents of the Azadirachta indica Plant
by: Areh E.T., et al.
Published: (2022-09-01)

Incompatibility of antimalarial drugs: challenges in formulating combination products for malaria
by: Ellen K. G. Mhango, et al.
Published: (2024-12-01)

Synthetic Analogs of the Alkaloid Cassiarin A with Enhanced Antimalarial Activity
by: Thomas Klaßmüller, et al.
Published: (2025-07-01)

Kaempferol Addition Increases the Antimalarial Activity of Artesunate in Experimental Mice
by: Sakaewan Ounjaijean, et al.
Published: (2020-01-01)

Cajachalcone: An Antimalarial Compound from Cajanus cajan Leaf Extract
by: E. O. Ajaiyeoba, et al.
Published: (2013-01-01)

A comprehensive review of antimalarial medicinal plants used by Tanzanians
by: David Sylvester Kacholi
Published: (2024-12-01)

Antimalarial compounds exhibit variant- and cell-type-specific activity against SARS-CoV-2 isolated in Panama
by: Mario Quijada, et al.
Published: (2025-06-01)

ANTIMALARIAL DRUGS IN THERAPY OF SYSTEMIC LUPUS ERYTHEMATOSUS: PAST, PRESENT, FUTURE
by: Tatyana Andreyevna Lisitsyna, et al.
Published: (2010-06-01)

A comprehensive revision on the use of quinoline antimalarial drugs as leishmanicidal agents
by: Romina E. Avanzo, et al.
Published: (2025-05-01)

Antimalarial Efficacy and Toxicological Assessment of Extracts of Some Ghanaian Medicinal Plants
by: Michael Konney Laryea, et al.
Published: (2019-01-01)

Antioxidant Potential of a Polyherbal Antimalarial as an Indicator of Its Therapeutic Value
by: Protus Arrey Tarkang, et al.
Published: (2013-01-01)

In silico antimalarial bioprospecting of neem (Azadirachta indica) quinine-derivative alkaloids
by: Alfin Hidayat, et al.
Published: (2025-04-01)

Guanine derivatives as promising candidates for the development of purine-based antimalarial drugs
by: Worlanyo Tashie, et al.
Published: (2025-07-01)

Transmission-blocking activity of antimalarials for Plasmodium vivax malaria in Anopheles darlingi.
by: Alice O Andrade, et al.
Published: (2023-06-01)

Nanoformulation and Preclinical Evaluation of Dihydroartemisinin–Lumefantrine and Primaquine as Combined Antimalarial Therapy
by: Pesila Odera, et al.
Published: (2025-01-01)

A reaction-diffusion system modeling the spread of resistance to an antimalarial drug
by: Nicolas Bacaër, et al.
Published: (2005-02-01)

Correction: Biogenically synthesized green silver nanoparticles exhibit antimalarial activity
by: Savitri Tiwari, et al.
Published: (2024-10-01)

Leveraging Digital Innovations to Combat Antimalarial Resistance in South and East Africa
by: Dr Stephanie Van Wyk, et al.
Published: (2025-03-01)

Broad thumbs and broad hallux: the hallmarks for the Rubinstein-Taybi syndrome
by: Carolina Candeias da Silva, et al.
Published: (2014-01-01)

Mathematical modelling and optimal control of malaria transmission with antimalarial drug and insecticide resistance
by: Gasper G. Mwanga
Published: (2025-12-01)

Public Awareness and Identification of Counterfeit Drugs in Tanzania: A View on Antimalarial Drugs
by: Linus Mhando, et al.
Published: (2016-01-01)

Exploring the Therapeutic Potential of Traditional Antimalarial and Antidengue Plants: A Mechanistic Perspective
by: Chinnaperumal Kamaraj, et al.
Published: (2023-01-01)

Antimalarial drug resistance and drug discovery: learning from the past to innovate the future
by: Liana Theodoridis, et al.
Published: (2025-08-01)

Adverse events in rheumatoid arthritis patients under antimalarial treatment—Is there cardiovascular compromise?
by: Pedro Santos-Moreno, et al.
Published: (2023-01-01)

Antimalarial Potential of Carica papaya and Vernonia amygdalina in Mice Infected with Plasmodium berghei
by: Oche Okpe, et al.
Published: (2016-01-01)

Assessing the quality of antimalarial drugs in Equatorial Guinea: a follow-up study
by: Harparkash Kaur, et al.
Published: (2025-07-01)

Investigation of antimalarial activity and cytotoxicity profiling of a Bangladeshi plant Syzygium cymosum
by: Muhammad Riadul Haque Hossainey, et al.
Published: (2020-08-01)

Synthesis and in vitro/in silico evaluation of the antimalarial activity of potential amino-quinoline derivatives
by: Moussa Touré, et al.
Published: (2025-04-01)